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- Title
Lymphomatoid papulosis. Case report providing evidence for a monocyte-macrophage origin of the atypical cells.
- Authors
Poppema, Sibrand; van Voorst Vader, Pieter C.; Rozeboom-Uiterwijk, Thea; Dijkstra, Jan W. E.; Poppema, S; van Voorst Vader, P C; Rozeboom-Uiterwijk, T; Dijkstra, J W
- Abstract
A patient with "classical" lymphomatoid papulosis is described in whom self-healing tumorous lesions occurred. Histologic, immunologic, enzyme histochemical and ultrastructural studies were performed. The atypical cells were found to be of monocyte-macrophage origin. The infiltrate also contained a variable number of suppressor-cytotoxic T-lymphocytes, depending on the stage of the tumorous lesions. The number of IgA positive B-lymphocytes in the peripheral blood was increased. The findings indicate that "classical" lymphomatoid papulosis is not a cutaneous T-cell lymphoma, but is the expression of an abnormal, immune reaction in the skin.
- Publication
Cancer (0008543X), 1983, Vol 52, Issue 7, p1178
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19831001)52:7<1178::AID-CNCR2820520709>3.0.CO;2-J