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Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.
Published in:
Cephalalgia, 2010, v. 30, n. 10, p. 1159, doi. 10.1177/0333102410370873
By:
- Nelson, David L;
- Phebus, Lee A;
- Johnson, Kirk W;
- Wainscott, David B;
- Cohen, Marlene L;
- Calligaro, David O;
- Xu, Yao-Chang
Publication type:
Article
In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders.
Published in:
Psychopharmacology, 2006, v. 185, n. 2, p. 240, doi. 10.1007/s00213-005-0292-0
By:
- Alt, Andrew;
- Weiss, Brianne;
- Ogden, Ann;
- Xia Li;
- Gleason, Scott D.;
- Calligaro, David O.;
- Bleakman, David;
- Witkin, Jeffrey M.
Publication type:
Article
β-Amyloid (25-35) or Substance P Stimulates [3H]MK-801. Binding to Rat Cortical Membranes in the Presence of Glutamate and Glycine.
Published in:
Journal of Neurochemistry, 1993, v. 60, n. 6, p. 2297, doi. 10.1111/j.1471-4159.1993.tb03517.x
By:
- Calligaro, David O.;
- O'Malley, Patrick J.;
- Monn, James A.
Publication type:
Article
Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease.
Published in:
Drug Development Research, 1997, v. 40, n. 2, p. 158, doi. 10.1002/(SICI)1098-2299(199702)40:2<158::AID-DDR6>3.0.CO;2-K
By:
- Bymaster, Frank P.;
- Whitesitt, Celia A.;
- Shannon, Harlan E.;
- DeLapp, Neil;
- Ward, John S.;
- Calligaro, David O.;
- Shipley, Lisa A.;
- Buelke-Sam, Judith L.;
- Bodick, Neil C.;
- Farde, Lars;
- Sheardown, Malcolm J.;
- Olesen, Preben H.;
- Hansen, Kristian T.;
- Suzdak, Peter D.;
- Swedberg, Michael D.B.;
- Sauerberg, Per;
- Mitch, Charles H.
Publication type:
Article
Pharmacological profile of LY301317, a potent and selective 5-HT1A agonist.
Published in:
Drug Development Research, 1997, v. 40, n. 1, p. 17, doi. 10.1002/(SICI)1098-2299(199701)40:1<17::AID-DDR2>3.0.CO;2-W
By:
- Wolff, Mary C.;
- Benvenga, Mark J.;
- Calligaro, David O.;
- Fuller, Ray W.;
- Gidda, Jaswant S.;
- Hemrick-Luecke, Susan;
- Lucot, James B.;
- Nelson, David L.;
- Overshiner, Carl D.;
- Leander, J. David
Publication type:
Article
Pharmacological characterization of enantiomers of 8-thiomethyl-2-(di-n-propylamino)tetralin, potent and selective 5-HT1A receptor agonists.
Published in:
Drug Development Research, 1995, v. 34, n. 1, p. 66, doi. 10.1002/ddr.430340110
By:
- Foreman, Mark M.;
- Fuller, Ray W.;
- Leander, J. David;
- Nelson, David L.;
- Calligaro, David O.;
- Lucaites, Virginia L.;
- Wong, David T.;
- Zhang, L.;
- Barrett, James E.;
- Schaus, John M.
Publication type:
Article
A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data.
Published in:
International Journal of Geriatric Psychiatry, 2001, v. 16, p. S33, doi. 10.1002/1099-1166(200112)16:1+<::AID-GPS571>3.0.CO;2-5
By:
- Kennedy, John S.;
- Bymaster, Frank P.;
- Schuh, Leslie;
- Calligaro, David O.;
- Nomikos, George;
- Felder, Christian C.;
- Bernauer, Mark;
- Kinon, Bruce J.;
- Baker, Robert W.;
- Hay, Donald;
- Roth, H. John;
- Dossenbach, Martin;
- Kaiser, Christopher;
- Beasley, Charles M.;
- Holcombe, John H.;
- Effron, Mark B.;
- Breier, Alan
Publication type:
Article
The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans.
Published in:
Journal of Neuroscience, 2015, v. 35, n. 3, p. 1199, doi. 10.1523/JNEUROSCI.4129-14.2015
By:
- May, Patrick C.;
- Willis, Brian A.;
- Lowe, Stephen L.;
- Dean, Robert A.;
- Monk, Scott A.;
- Cocke, Patrick J.;
- Audia, James E.;
- Boggs, Leonard N.;
- Borders, Anthony R.;
- Brier, Richard A.;
- Calligaro, David O.;
- Day, Theresa A.;
- Ereshefsky, Larry;
- Erickson, Jon A.;
- Gevorkyan, Hykop;
- Gonzales, Celedón R.;
- James, Douglas E.;
- Jhee, Stanford S.;
- Komjathy, Steven F.;
- Li, Linglin
Publication type:
Article
Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor.
Published in:
Journal of Neuroscience, 2011, v. 31, n. 46, p. 16507, doi. 10.1523/JNEUROSCI.3647-11.2011
By:
- May, Patrick C.;
- Dean, Robert A.;
- Lowe, Stephen L.;
- Martenyi, Ferenc;
- Sheehan, Scott M.;
- Boggs, Leonard N.;
- Monk, Scott A.;
- Mathes, Brian M.;
- Mergott, Dustin J.;
- Watson, Brian M.;
- Stout, Stephanie L.;
- Timm, David E.;
- LaBell, Elizabeth Smith;
- Gonzales, Celedon R.;
- Nakano, Masako;
- Jhee, Stanford S.;
- Yen, Mark;
- Ereshefsky, Larry;
- Lindstrom, Terry D.;
- Calligaro, David O.
Publication type:
Article

Found: 9

Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan.

In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders.

β-Amyloid (25-35) or Substance P Stimulates [<sup>3</sup>H]MK-801. Binding to Rat Cortical Membranes in the Presence of Glutamate and Glycine.

Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease.

Pharmacological profile of LY301317, a potent and selective 5-HT<sub>1A</sub> agonist.

Pharmacological characterization of enantiomers of 8-thiomethyl-2-(di-n-propylamino)tetralin, potent and selective 5-HT<sub>1A</sub> receptor agonists.

A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data.

The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans.

Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor.