We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Primary pulmonary diffuse large B-cell lymphoma associated with feline leukaemia virus infection in a young cat.
- Authors
Ishikawa, Kento; Nagashima, Tomokazu; Machida, Yukino; Yasuda, Akiko; Yoshida, Karin; Fujita, Michio; Ochiai, Kazuhiko; Azakami, Daigo; Michishita, Masaki
- Abstract
Case summary: A 4-year-old castrated male domestic shorthair cat with a continuous cough was brought to a private veterinary clinic for detailed examination. Radiography of the thoracic cavity revealed a severe radiopaque region in the caudal lobe of the right lung. At 108 days after the initial visit, CT showed a mass of 27 × 23 × 18 mm in the caudal lobe of the right lung. At that time, no abnormalities in other organs except for the lung were detected on CT and peripheral blood and blood biochemistry tests. The mass in the caudal lobe of the right lung was resected by lobectomy; it had a white surface and was firm. Histopathologically, the mass was non-encapsulated, showing an unclear boundary with surrounding tissues. The mass comprised large, round or polygonal neoplastic cells arranged in a diffuse pattern. Immunohistochemically, neoplastic cells were diffusely positive for CD20, feline leukaemia virus (FeLV) p27 and FeLV glycoprotein 70 but negative for CD3, CD204 and E-cadherin. Based on these findings, diffuse large B-cell lymphoma associated with FeLV infection was diagnosed. Although the cat showed no clinical signs of gastrointestinal or respiratory injury, a routine ultrasonography revealed thickening in the jejunum wall 196 days after lobectomy, and subsequent fine-needle aspiration examination confirmed high-grade lymphoma. Relevance and novel information: This is the first report of primary pulmonary diffuse large B-cell lymphoma associated with FeLV infection in a young cat.
- Publication
Journal of Feline Medicine & Surgery Open Reports, 2022, Vol 8, Issue 1, p1
- ISSN
2055-1169
- Publication type
Article
- DOI
10.1177/20551169221074240