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- Title
Detection of the Single-Session Complete Ablation Rate by Contrast-Enhanced Ultrasound during Ultrasound-Guided Laser Ablation for Benign Thyroid Nodules: A Prospective Study.
- Authors
Ma, Shuhua; Zhou, Ping; Wu, Xiaomin; Tian, Shuangming; Zhao, Yongfeng
- Abstract
This study aimed to investigate the single-session complete ablation rate of ultrasound-guided percutaneous laser ablation (LA) for benign thyroid nodules. LA was performed in 90 patients with 118 benign thyroid nodules. Contrast-enhanced ultrasound (CEUS) was used to evaluate complete nodule ablation one day after ablation. Thyroid nodule volumes, thyroid functions, clinical symptoms and complications were evaluated 1, 3, 6, 12, and 18 months after ablation. Results showed that all benign thyroid nodules successfully underwent LA. The single-session complete ablation rates for nodules with maximum diameters ≤2 cm, 2-3 cm and ≥3 cm were 93.4%, 70.3% and 61.1%, respectively. All nodule volumes significantly decreased than that one day after ablation (P<0.05); at the final evaluation, the volume decreased from 6.16±5.21 mL to 0.05±0.01 mL. Thyroid functions did not show significant differences at one month after ablation compared with that before (P>0.05). Three patients had obvious pain during ablation; one (1.1%) had recurrent laryngeal nerve injury, but the voice returned to normal within 6 months after treatment. Thus, ultrasound-guided LA can effectively inactivate benign thyroid nodules. LA is a potentially viable minimally invasive treatment that offers good cosmetic effects.
- Subjects
CHINA; THYROID gland physiology; LARYNGEAL nerve injuries; ACADEMIC medical centers; CHI-squared test; ENDOSCOPIC surgery; MEDICAL lasers; LONGITUDINAL method; COMPUTERS in medicine; PAIN; PREOPERATIVE care; PROBABILITY theory; RESEARCH funding; SURGICAL complications; T-test (Statistics); THERAPEUTICS; THYROID gland tumors; WEIGHTS &; measures; TREATMENT effectiveness; CONTRAST media; ABLATION techniques; DATA analysis software; DESCRIPTIVE statistics; TUMOR treatment
- Publication
BioMed Research International, 2016, Vol 2016, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2016/9565364