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- Title
The COVIRL-001 Trial: A multicentre, prospective, randomised trial comparing standard of care (SOC) alone, SOC plus hydroxychloroquine monotherapy or SOC plus a combination of hydroxychloroquine and azithromycin in the treatment of non- critical, SARS-CoV-2 PCR-positive population not requiring immediate resuscitation or ventilation but who have evidence of clinical decline: A structured summary of a study protocol for a randomised controlled trial.
- Authors
Feeney, Eoin; Wallace, Deborah; Cotter, Aoife; Tinago, Willard; McCarthy, Cormac; Keane, David; Hussain, Rabia; Alvarez Barco, Elena; Doran, Peter; Mallon, Patrick
- Abstract
SARS-CoV-2 PCR-positive population not requiring immediate resuscitation or ventilation but who have evidence of clinical decline: A structured summary of a study protocol for a randomised controlled trial Objectives Hydroxychloroquine has attracted considerable interest as a potential therapy for COVID-19 infection due to its immunomodulatory effects and reported efficiency in clearing upper airways of the virus. Recent data have also suggested the treatment of COVID-19 patients with hydroxychloroquine and azithromycin to cure the associated infection.
- Subjects
SARS-CoV-2; AZITHROMYCIN; RESUSCITATION; NASAL cannula
- Publication
Trials, 2020, Vol 21, Issue 1, p1
- ISSN
1745-6215
- Publication type
letter
- DOI
10.1186/s13063-020-04407-x