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Generation of synthetic PET images of synaptic density and amyloid from 18F‐FDG images using deep learning.
Published in:
Medical Physics, 2021, v. 48, n. 9, p. 5115, doi. 10.1002/mp.15073
By:
- Wang, Rui;
- Liu, Hui;
- Toyonaga, Takuya;
- Shi, Luyao;
- Wu, Jing;
- Onofrey, John Aaron;
- Tsai, Yu‐Jung;
- Naganawa, Mika;
- Ma, Tianyu;
- Liu, Yaqiang;
- Chen, Ming‐Kai;
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- van Dyck, Christopher H.;
- Carson, Richard E.;
- Liu, Chi
Publication type:
Article
Glutamate Carboxypeptidase II in Aging Rat Prefrontal Cortex Impairs Working Memory Performance.
Published in:
Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.760270
By:
- Datta, Dibyadeep;
- Leslie, Shannon N.;
- Woo, Elizabeth;
- Amancharla, Nishita;
- Elmansy, Ayah;
- Lepe, Miguel;
- Mecca, Adam P.;
- Slusher, Barbara S.;
- Nairn, Angus C.;
- Arnsten, Amy F. T.
Publication type:
Article
Sex differences in the pleiotropy of hearing difficulty with imaging-derived phenotypes: a brain-wide investigation.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 10, p. 3395, doi. 10.1093/brain/awae077
By:
- He, Jun;
- Cabrera-Mendoza, Brenda;
- Angelis, Flavio De;
- Pathak, Gita A;
- Koller, Dora;
- Curhan, Sharon G;
- Curhan, Gary C;
- Mecca, Adam P;
- Dyck, Christopher H van;
- Polimanti, Renato
Publication type:
Article
CT1812 biomarker signature from a meta‐analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 10, p. 6860, doi. 10.1002/alz.14152
By:
- Lizama, Britney N.;
- Williams, Claire;
- North, Hilary A.;
- Pandey, Kiran;
- Duong, Duc;
- Di Caro, Valentina;
- Mecca, Adam P.;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Levey, Allan I.;
- Grundman, Michael;
- van Dyck, Christopher H.;
- Caggiano, Anthony O.;
- Seyfried, Nicholas T.;
- Hamby, Mary E.
Publication type:
Article
Tau epicenter identification and connectivity in clinically heterogeneous Alzheimer's disease variants.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079435
By:
- Trainer, Anne;
- Xu, Wanwan;
- Chase, Alison;
- O'Dell, Ryan S.;
- Tun, Samantha M;
- Li, Joyce S;
- Ju, Suyeon;
- van Dyck, Christopher H;
- Mecca, Adam P;
- Fredricks, Carolyn
Publication type:
Article
IC‐04‐03: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P8, doi. 10.1016/j.jalz.2018.06.2051
By:
- Mecca, Adam P.;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Godek, Tyler;
- Harris, Joanna;
- Chen, Ming-Kai;
- Nabulsi, Nabeel B.;
- Salardini, Arash;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
CSF proteomics analysis to investigate the pharmacodynamic response of the S2R modulator CT1812 in Alzheimer's disease patients from the SPARC clinical trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068166
By:
- Pandey, Kiran;
- Waybright, Lora;
- Duong, Duc M.;
- Malagise, Evi;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Mecca, Adam P;
- van Dyck, Christopher H;
- Caggiano, Anthony O;
- Seyfried, Nicholas T.;
- Hamby, Mary E
Publication type:
Article
Assessment of gray matter microstructure and synaptic density in Alzheimer's Disease: a multimodal imaging study with DWI and SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065064
By:
- Salardini, Elaheh;
- Silva‐Rudberg, Jason A;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Ra, Jocelyn;
- Georgelos, Jamie K;
- Morehouse, Mackenzie R;
- Melino, Kaitlyn P;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H;
- Mecca, Adam P
Publication type:
Article
Association of synaptic density and glucose metabolism with cognitive performance in early Alzheimer's disease: a PET imaging study with [11C]UCB‐J and [18F]FDG.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.062595
By:
- O'Dell, Ryan S.;
- Mecca, Adam P;
- Waszak, Julia;
- Sharp, Emily;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Lu, Yihuan;
- Chupak, Anna;
- Cooper, Emma;
- Lam, Jessica;
- Miller, Alyssa;
- Waldner, Emma;
- Weibley, Hannah;
- Zhao, Yize;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F. T.;
- Carson, Richard E.;
- van Dyck, Christopher H
Publication type:
Article
Investigating a CD8+ T cell age‐associated gene signature in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.064384
By:
- Young, Juan J;
- Park, Hong‐Jai;
- Par‐Young, Jennefer;
- Bartlett, Hugh H.;
- Kim, Hye Sun;
- Shin, Min Sun;
- You, Sungyong;
- Kim, Min Hyung;
- Allore, Heather G.;
- Mecca, Adam P;
- Kang, Insoo
Publication type:
Article
Assessment of gray matter microstructure and synaptic density in Alzheimer's Disease: a multimodal imaging study with DWI and SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.065162
By:
- Salardini, Elaheh;
- Silva‐Rudberg, Jason A;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Ra, Jocelyn;
- Georgelos, Jamie K;
- Morehouse, Mackenzie R;
- Melino, Kaitlyn P;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H;
- Mecca, Adam P
Publication type:
Article
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 12, p. 2527, doi. 10.1002/alz.12582
By:
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- Sharp, Emily S.;
- Banks, Emmie R.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Lipior, Sylwia;
- Diepenbrock, Nina G.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Nabulsi, Nabeel B.;
- Vander Wyk, Brent C.;
- Arnsten, Amy F. T.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
Synaptic density is associated with cognitive performance in Alzheimer’s disease: A PET imaging study with [11C]UCB‐J.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054213
By:
- van Dyck, Christopher H.;
- Sharp, Emily;
- O'Dell, Ryan S.;
- Banks, Emmie R.;
- Bartlett, Hugh H.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Harris, Joanna E.;
- Ni, Gessica S.;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Wyk, Brent C. Vander;
- Huang, Yiyun;
- Arnsten, Amy F. T.;
- Carson, Richard E.;
- Mecca, Adam P.
Publication type:
Article
Cerebrospinal fluid and brain PET measures of synaptic density glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054831
By:
- Mecca, Adam P.;
- Ashton, Nicholas J.;
- Chen, Ming‐Kai;
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Brinkmalm, Ann;
- Kvartsberg, Hlin;
- Schöll, Michael;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Carson, Richard E.;
- van Dyck, Christopher H.;
- Nilsson, Johanna
Publication type:
Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 2, p. 316, doi. 10.1002/alz.12190
By:
- Mecca, Adam P.;
- Dyck, Christopher H.
Publication type:
Article
Validation of a simplified tissue‐to‐reference ratio measurement using SUVR for the assessment of synaptic density alterations in Alzheimer's disease using [11C]UCB‐J PET: Neuroimaging / New imaging methods.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045928
By:
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Young, Juan;
- Dahal, Rabin;
- Singh, Edward;
- Waheed, Aisha;
- Banks, Emmie R.;
- Harris, Joanna E.;
- Chen, Ming‐Kai;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.;
- Mecca, Adam P.
Publication type:
Article
Association between cerebrospinal fluid biomarkers of neurodegeneration and PET measurements of synaptic density in Alzheimer's disease: Neuroimaging / multi‐modal comparisons.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044211
By:
- Mecca, Adam P.;
- Ashton, Nicholas J;
- Chen, Ming‐Kai;
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Banks, Emmie R.;
- Kominek, Victoria L.;
- Nabulsi, Nabeel B.;
- Najafzadeh, Soheila;
- Wyk, Brent C. Vander;
- Brinkmalm, Ann;
- Kvartsberg, Hlin;
- Schöll, Michael;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Blennow, Kaj;
- Zetterberg, Henrik
Publication type:
Article
Association between cerebral amyloid accumulation and synaptic density in Alzheimer's disease: A multitracer PET study: Neuroimaging: Imaging the human synapse in AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043631
By:
- O'Dell, Ryan S.;
- Mecca, Adam P.;
- Chen, Ming‐Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Banks, Emmie R.;
- Kominek, Victoria L.;
- Zhao, Wenzhen;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Lu, Yihuan;
- Nabulsi, Nabeel B.;
- Ropchan, Jim R;
- Ye, Yunpeng;
- Vander Wyk, Brent C.;
- Varma, Pradeep;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Carson, Richard E.
Publication type:
Article
11C‐PBR28 brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer's disease: Neuroimaging / New imaging methods.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043584
By:
- Salardini, Arash;
- Hillmer, Ansel T;
- Mecca, Adam P;
- Hashemi‐Aghdam, Arsalan;
- Laltoo, Emily;
- Savoia, Sarah;
- O'Dell, Ryan S;
- Harris, Joanna E;
- Godek, Tyler A.;
- Nabulsi, Nabeel B;
- Lim, Keunpoong;
- Ropchan, Jim R;
- Huang, Yiyun;
- Cosgrove, Kelly;
- Carson, Richard E;
- Strittmatter, Stephen M;
- van Dyck, Christopher H
Publication type:
Article
ICA‐derived sources of synaptic density PET ([11C]UCB‐J) relate to cognitive impairment severity in Alzheimer's disease: Neuroimaging: Imaging the human synapse in AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041197
By:
- Fang, Xiaotian T.;
- Mecca, Adam P.;
- Naganawa, Mika;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- van Dyck, Christopher H.;
- Carson, Richard E.
Publication type:
Article
PBR28 Brain PET imaging with lipopolysaccharide challenge for the study of microglia function in Alzheimer's disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037792
By:
- Salardini, Arash;
- Hillmer, Ansel T.;
- Mecca, Adam P.;
- Hashemi‐Aghdam, Arsalan;
- Laltoo, Emily;
- Savoia, Sarah;
- O'Dell, Ryan S.;
- Harris, Joanna E.;
- Godek, Tyler A.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Cosgrove, Kelly;
- Carson, Richard E.;
- Strittmatter, Stephen M;
- van Dyck, Christopher H.
Publication type:
Article
In vivo measurement of widespread synaptic loss and associated tau accumulation in early Alzheimer's disease: Molecular imaging of novel biomarkers for neurodegeneration and ADRD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037791
By:
- Mecca, Adam P.;
- O'Dell, Ryan S.;
- Chen, Ming‐Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Gallezot, Jean‐Dominique;
- Nabulsi, Nabeel B.;
- Ropchan, Jim R.;
- Ye, Yunpeng;
- Wyk, Brent C. Vander;
- Arnsten, Amy F.T.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 974, doi. 10.1002/alz.12097
By:
- Mecca, Adam P.;
- Chen, Ming‐Kai;
- O'Dell, Ryan S.;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Wyk, Brent C. Vander;
- Varma, Pradeep;
- Arnsten, Amy F. T.;
- Huang, Yiyun;
- Carson, Richard E.;
- Dyck, Christopher H.
Publication type:
Article
P4‐481: ASSOCIATION BETWEEN ENTORHINAL CORTICAL TAU ACCUMULATION AND HIPPOCAMPAL SYNAPTIC DENSITY IN OLDER INDIVIDUALS WITH NORMAL COGNITION AND EARLY ALZHEIMER'S DISEASE: PRELIMINARY EXPERIENCE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1497, doi. 10.1016/j.jalz.2019.08.027
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Gallezot, Jean-Dominique;
- Charil, Arnaud;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F.T.;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
P2‐349: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY OF HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P729, doi. 10.1016/j.jalz.2019.06.2756
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐P‐140: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY IN HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4254
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐P‐140: ASSOCIATION BETWEEN MGLUR5 AND SYNAPTIC DENSITY: A MULTI‐TRACER STUDY IN HEALTHY AGING AND ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P115, doi. 10.1016/j.jalz.2019.06.4254
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Toyonaga, Takuya;
- Naganawa, Mika;
- Salardini, Arash;
- Arnsten, Amy F.T.;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Najafzadeh, Soheila;
- Ropchan, Jim R.;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
P2‐365: PET IMAGING OF SYNAPTIC DENSITY (SYNAPTIC VESICLE GLYCOPROTEIN 2A, SV2A) IN ALZHEIMER'S DISEASE: INITIAL EXPERIENCE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P832, doi. 10.1016/j.jalz.2018.06.1056
By:
- Chen, Ming-Kai;
- Mecca, Adam P.;
- Naganawa, Mika;
- Finnema, Sjoerd J.;
- Toyonaga, Takuya;
- Gallezot, Jean-Dominique;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F.T.;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
P1‐469: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P501, doi. 10.1016/j.jalz.2018.06.479
By:
- Mecca, Adam P.;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Godek, Tyler;
- Harris, Joanna;
- Chen, Ming-Kai;
- Nabulsi, Nabeel B.;
- Salardini, Arash;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐P‐183: PET IMAGING OF SYNAPTIC DENSITY (SYNAPTIC VESICLE GLYCOPROTEIN 2A, SV2A) IN ALZHEIMER'S DISEASE: INITIAL EXPERIENCE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P152, doi. 10.1016/j.jalz.2018.06.2250
By:
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Naganawa, Mika;
- Finnema, Sjoerd J.;
- Toyonaga, Takuya;
- Lin, Shu-fei;
- Gallezot, Jean-Dominique;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Nabulsi, Nabeel B.;
- Huang, Yiyun;
- Arnsten, Amy F.T.;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
IC‐04‐03: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P8, doi. 10.1016/j.jalz.2018.06.2051
By:
- Mecca, Adam P.;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Godek, Tyler;
- Harris, Joanna;
- Chen, Ming-Kai;
- Nabulsi, Nabeel B.;
- Salardini, Arash;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [11C]UCB-J.
Published in:
Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-020-00742-y
By:
- O'Dell, Ryan S.;
- Mecca, Adam P.;
- Chen, Ming-Kai;
- Naganawa, Mika;
- Toyonaga, Takuya;
- Lu, Yihuan;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Bartlett, Hugh H.;
- Banks, Emmie R.;
- Kominek, Victoria L.;
- Zhao, Wenzhen;
- Nabulsi, Nabeel B.;
- Ropchan, Jim;
- Ye, Yunpeng;
- Vander Wyk, Brent C.;
- Huang, Yiyun;
- Arnsten, Amy F. T.;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
PET imaging of mGluR5 in Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-0582-0
By:
- Mecca, Adam P.;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Godek, Tyler A.;
- Harris, Joanna E.;
- Pugh, Erika A.;
- Kemp, Emily C.;
- Chen, Ming-Kai;
- Salardini, Arash;
- Nabulsi, Nabeel B.;
- Lim, Keunpoong;
- Huang, Yiyun;
- Carson, Richard E.;
- Strittmatter, Stephen M.;
- van Dyck, Christopher H.
Publication type:
Article
Amyloid burden is associated with decreased gray matter volume but not episodic memory performance in cognitively normal first-degree relatives at varying ApoE4 risk for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P680, doi. 10.1016/j.jalz.2015.06.123
By:
- van Dyck, Christopher H.;
- Mecca, Adam P.;
- Wang, Shuo;
- Barcelos, Nicole M.;
- Planeta-Wilson, Beata;
- Gelernter, Joel;
- Van Ness, Peter;
- Carson, Richard E.
Publication type:
Article
Amyloid burden is associated with decreased gray matter volume but not episodic memory performance in cognitively normal first-degree relatives at varying ApoE4 risk for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P69, doi. 10.1016/j.jalz.2015.06.123
By:
- van Dyck, Christopher H.;
- Mecca, Adam P.;
- Wang, Shuo;
- Barcelos, Nicole M.;
- Planeta-Wilson, Beata;
- Gelernter, Joel;
- Van Ness, Peter;
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Article
Sleep Disturbance and the Risk of Cognitive Decline or Clinical Conversion in the ADNI Cohort.
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Dementia & Geriatric Cognitive Disorders, 2018, v. 45, n. 3/4, p. 232, doi. 10.1159/000488671
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- Michalak, Hannah R.;
- McDonald, Julia W.;
- Kemp, Emily C.;
- Pugh, Erika A.;
- Becker, Melinda L.;
- Mecca, Adam P.;
- van Dyck, Christopher H.;
- Mecca, Marcia C.
Publication type:
Article
Comparison of [ 11 C]UCB-J and [ 18 F]FDG PET in Alzheimer's disease: A tracer kinetic modeling study.
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Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 9, p. 2395, doi. 10.1177/0271678X211004312
By:
- Chen, Ming-Kai;
- Mecca, Adam P;
- Naganawa, Mika;
- Gallezot, Jean-Dominique;
- Toyonaga, Takuya;
- Mondal, Jayanta;
- Finnema, Sjoerd J;
- Lin, Shu-fei;
- O'Dell, Ryan S;
- McDonald, Julia W;
- Michalak, Hannah R;
- Vander Wyk, Brent;
- Nabulsi, Nabeel B;
- Huang, Yiyun;
- Arnsten, Amy FT;
- van Dyck, Christopher H;
- Carson, Richard E
Publication type:
Article
Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.
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JAMA Neurology, 2018, v. 75, n. 10, p. 1215, doi. 10.1001/jamaneurol.2018.1836
By:
- Chen, Ming-Kai;
- Mecca, Adam P.;
- Naganawa, Mika;
- Finnema, Sjoerd J.;
- Toyonaga, Takuya;
- Lin, Shu-fei;
- Najafzadeh, Soheila;
- Ropchan, Jim;
- Lu, Yihuan;
- McDonald, Julia W.;
- Michalak, Hannah R.;
- Nabulsi, Nabeel B.;
- Arnsten, Amy F. T.;
- Huang, Yiyun;
- Carson, Richard E.;
- van Dyck, Christopher H.
Publication type:
Article
Angiotensin-(1-7) prevents cardiac remodeling during angiotensin II- induced hypertension.
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FASEB Journal, 2007, v. 21, n. 6, p. A896, doi. 10.1096/fasebj.21.6.a896-d
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- Shenoy, Vinayak;
- Bolton, Tonya A.;
- Machado, Juline M.;
- Speth, Robert C.;
- Raizada, Mohan K.;
- Katovich, Michael J.
Publication type:
Article
Aging gene signature of memory CD8+ T cells is associated with neurocognitive functioning in Alzheimer's disease.
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Immunity & Ageing, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12979-023-00396-y
By:
- Young, Juan Joseph;
- Park, Hong-Jai;
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- Par-Young, Jennefer;
- Bartlett, Hugh;
- Kim, Hye Sun;
- Unlu, Serhan;
- Osmani, Lais;
- Shin, Min Sun;
- Bucala, Richard;
- van Dyck, Christopher H.;
- Allore, Heather;
- Mecca, Adam P.;
- You, Sungyong;
- Kang, Insoo
Publication type:
Article
Synaptic density patterns in early Alzheimer's disease assessed by independent component analysis.
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Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae107
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- Naganawa, Mika;
- Mecca, Adam P;
- Chen, Ming-Kai;
- Dyck, Christopher H van;
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Publication type:
Article
Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression.
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Human Molecular Genetics, 2021, v. 30, n. 14, p. 1360, doi. 10.1093/hmg/ddab102
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- Gelernter, Joel;
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Publication type:
Article
Assessing an Interprofessional Polypharmacy and Deprescribing Educational Intervention for Primary Care Post-graduate Trainees: a Quantitative and Qualitative Evaluation.
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2019
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- Mecca, Marcia C.;
- Thomas, John M.;
- Niehoff, Kristina M.;
- Hyson, Anne;
- Jeffery, Sean M.;
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- Mecca, Adam P.;
- Van Ness, Peter H.;
- Fried, Terri R.;
- Brienza, Rebecca
Publication type:
journal article
Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials.
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Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2023, v. 9, n. 2, p. 1, doi. 10.1002/trc2.12388
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- Van Dyck, Christopher H.;
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Publication type:
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Centrally administered angiotensin-(1-7) increases the survival of stroke-prone spontaneously hypertensive rats.
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Experimental Physiology, 2014, v. 99, n. 2, p. 442, doi. 10.1113/expphysiol.2013.075242
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- Mecca, Adam P.;
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- Ritucci-Chinni, Phillip F.;
- Ludin, Jacob A.;
- Greenstein, David;
- Banuelos, Cristina;
- Bizon, Jennifer L.;
- Reinhard, Mary K.;
- Sumners, Colin
Publication type:
Article
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
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Experimental Physiology, 2011, v. 96, n. 10, p. 1084, doi. 10.1113/expphysiol.2011.058578
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- Mecca, Adam P.;
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- O'Connor, Timothy E.;
- Joseph, Jason P.;
- Raizada, Mohan K.;
- Katovich, Michael J.;
- Sumners, Colin
Publication type:
Article
Candesartan pretreatment is cerebroprotective in a rat model of endothelin-1-induced middle cerebral artery occlusion.
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Experimental Physiology, 2009, v. 94, n. 8, p. 937, doi. 10.1113/expphysiol.2009.047936
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- Mecca, Adam P.;
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- Katovich, Michael J.;
- Sumners, Colin
Publication type:
Article
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.
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Experimental Physiology, 2005, v. 90, n. 5, p. 783, doi. 10.1113/expphysiol.2005.031096
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- Huentelman, Matthew J.;
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- Vazquez, Jorge;
- Stewart, Jillian M.;
- Mecca, Adam P.;
- Katovich, Michael J.;
- Ferrario, Carlos M.;
- Raizada, Mohan K.
Publication type:
Article
A pilot study to evaluate the effect of CT1812 treatment on synaptic density and other biomarkers in Alzheimer's disease.
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Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01382-2
By:
- van Dyck, Christopher H.;
- Mecca, Adam P.;
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- Bartlett, Hugh H.;
- Diepenbrock, Nina G.;
- Huang, Yiyun;
- Hamby, Mary E.;
- Grundman, Michael;
- Catalano, Susan M.;
- Caggiano, Anthony O.;
- Carson, Richard E.
Publication type:
Article
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 51, n. 4, p. 1012, doi. 10.1007/s00259-023-06487-8
By:
- Toyonaga, Takuya;
- Khattar, Nikkita;
- Wu, Yanjun;
- Lu, Yihuan;
- Naganawa, Mika;
- Gallezot, Jean-Dominique;
- Matuskey, David;
- Mecca, Adam P.;
- Pittman, Brian;
- Dias, Mark;
- Nabulsi, Nabeel B.;
- Finnema, Sjoerd J.;
- Chen, Ming-Kai;
- Arnsten, Amy;
- Radhakrishnan, Rajiv;
- Skosnik, Patrick D.;
- D'Souza, Deepak Cyril;
- Esterlis, Irina;
- Huang, Yiyun;
- van Dyck, Christopher H.
Publication type:
Article

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