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Evidence of cerebellar TDP-43 loss of function in FTLD-TDP.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01408-6
By:
- Pickles, Sarah;
- Gendron, Tania F.;
- Koike, Yuka;
- Yue, Mei;
- Song, Yuping;
- Kachergus, Jennifer M.;
- Shi, J.;
- DeTure, Michael;
- Thompson, E. Aubrey;
- Oskarsson, Björn;
- Graff-Radford, Neill R.;
- Boeve, Bradley F.;
- Petersen, Ronald C.;
- Wszolek, Zbigniew K.;
- Josephs, Keith A.;
- Dickson, Dennis W.;
- Petrucelli, Leonard;
- Cook, Casey N.;
- Prudencio, Mercedes
Publication type:
Article
MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-01097-z
By:
- Valentino, Rebecca R.;
- Koga, Shunsuke;
- Walton, Ronald L.;
- Soto-Beasley, Alexandra I.;
- Kouri, Naomi;
- DeTure, Michael A.;
- Murray, Melissa E.;
- Johnson, Patrick W.;
- Petersen, Ronald C.;
- Boeve, Bradley F.;
- Uitti, Ryan J.;
- Wszolek, Zbigniew K.;
- Dickson, Dennis W.;
- Ross, Owen A.;
- Heckman, Michael G.
Publication type:
Article
Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-01079-1
By:
- Wojtas, Aleksandra M.;
- Carlomagno, Yari;
- Sens, Jonathon P.;
- Kang, Silvia S.;
- Jensen, Tanner D.;
- Kurti, Aishe;
- Baker, Kelsey E.;
- Berry, Taylor J.;
- Phillips, Virginia R.;
- Castanedes, Monica Casey;
- Awan, Ayesha;
- DeTure, Michael;
- De Castro, Cristhoper H. Fernandez;
- Librero, Ariston L.;
- Yue, Mei;
- Daughrity, Lillian;
- Jansen-West, Karen R.;
- Cook, Casey N.;
- Dickson, Dennis W.;
- Petrucelli, Leonard
Publication type:
Article
Comprehensive characterization of human brain‐derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications.
Published in:
Journal of Extracellular Vesicles, 2023, v. 12, n. 8, p. 1, doi. 10.1002/jev2.12358
By:
- Zhang, Zhengrong;
- Yu, Kaiwen;
- You, Yang;
- Jiang, Peizhou;
- Wu, Zhiping;
- DeTure, Michael A.;
- Dickson, Dennis W.;
- Ikezu, Seiko;
- Peng, Junmin;
- Ikezu, Tsuneya
Publication type:
Article
Assembly of filamentous tau aggregates in human neuronal cells.
Published in:
Journal of Alzheimer's Disease, 2004, v. 6, n. 6, p. 605
By:
- Li-Wen Ko;
- Rush, Toni;
- Sahara, Naruhiko;
- Kersh, Jay S.;
- Easson, Colin;
- DeTure, Michael;
- Wen-Lang Lin;
- Connor, Yamicia D.;
- Yen, Shu-Hui C.
Publication type:
Article
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32951-4
By:
- Seidler, Paul M.;
- Murray, Kevin A.;
- Boyer, David R.;
- Ge, Peng;
- Sawaya, Michael R.;
- Hu, Carolyn J.;
- Cheng, Xinyi;
- Abskharon, Romany;
- Pan, Hope;
- DeTure, Michael A.;
- Williams, Christopher K.;
- Dickson, Dennis W.;
- Vinters, Harry V.;
- Eisenberg, David S.
Publication type:
Article
Investigating phenotypic modifiers of Alzheimer's disease utilizing cellular and transcriptomic signatures of PSEN1 mutation carriers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080082
By:
- Pottier, Cyril P;
- Lincoln, Sarah J.;
- Boon, Baayla D.C.;
- Wickland, Daniel P.;
- Rothberg, Darren M.;
- DeTure, Michael;
- Ertekin‐Taner, Nilufer;
- Graff‐Radford, Neill R;
- Dickson, Dennis W.;
- Murray, Melissa E.
Publication type:
Article
Uncovering Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach (BioID).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079920
By:
- Lee, Jannifer H;
- Morderer, Dmytro;
- Khalil, Bilal;
- Smith, Courtney L;
- Wren, Melissa C;
- Tsai, Chih‐Wei;
- Liu, Feilin;
- Croft, Cara L;
- Carlomagno, Yari;
- DeTure, Michael;
- Dickson, Dennis W.;
- Cook, Casey N.;
- Golde, Todd E;
- Petrucelli, Leonard;
- Rossoll, Wilfried
Publication type:
Article
Sex‐specific transcriptome alterations in the cingulate cortex of Lewy body dementia cases.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079987
By:
- Olney, Kimberly C.;
- Wojtas, Aleksandra;
- Rabichow, Benjamin E.;
- DeTure, Michael;
- Dickson, Dennis W.;
- Chang, Rui;
- Ross, Owen A.;
- Fryer, John D.
Publication type:
Article
Identification of novel genetic risk factors for cerebral amyloid angiopathy and characterization of the implicated LINC‐PINT locus.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077421
By:
- Atik, Merve;
- Reddy, Joseph S.;
- Nguyen, Thuy;
- Sotelo, Katie;
- Tutor‐New, Frederick Q;
- Carrasquillo, Minerva M.;
- DeTure, Michael;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Biochemical Evidence for a Pathological Variant of Progressive Supranuclear Palsy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076848
By:
- DeTure, Michael;
- Chalk, Jessica L;
- Murray, Melissa E.;
- Dickson, Dennis W.
Publication type:
Article
DNA methylation clustered by predicted chromatin state reveals distinct association patterns with neuropathologic and biochemical measures in the AD brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072470
By:
- Oatman, Stephanie R;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Sex‐specific transcriptome alterations in the cingulate cortex of Lewy body dementia cases.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079987
By:
- Olney, Kimberly C.;
- Wojtas, Aleksandra;
- Rabichow, Benjamin E.;
- DeTure, Michael;
- Dickson, Dennis W.;
- Chang, Rui;
- Ross, Owen A.;
- Fryer, John D.
Publication type:
Article
Identification of novel genetic risk factors for cerebral amyloid angiopathy and characterization of the implicated LINC‐PINT locus.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077421
By:
- Atik, Merve;
- Reddy, Joseph S.;
- Nguyen, Thuy;
- Sotelo, Katie;
- Tutor‐New, Frederick Q;
- Carrasquillo, Minerva M.;
- DeTure, Michael;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Biochemical Evidence for a Pathological Variant of Progressive Supranuclear Palsy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076848
By:
- DeTure, Michael;
- Chalk, Jessica L;
- Murray, Melissa E.;
- Dickson, Dennis W.
Publication type:
Article
DNA methylation clustered by predicted chromatin state reveals distinct association patterns with neuropathologic and biochemical measures in the AD brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072470
By:
- Oatman, Stephanie R;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Bu, Guojun;
- Dickson, Dennis W.;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Transcriptome profiling in AD cases to identify distinct associations with AD‐related neuropathology and protein levels in the brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067201
By:
- Allen, Mariet;
- Quicksall, Zachary;
- Wang, Xue;
- Reddy, Joseph S.;
- Bergman, Jeremiah;
- Oatman, Stephanie R;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Lincoln, Sarah J.;
- Yamazaki, Yu;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Liu, Chia‐Chen;
- Kanekiyo, Takahisa;
- Dickson, Dennis W.;
- Bu, Guojun;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Identification of Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065671
By:
- Lee, Jannifer H;
- Morderer, Dmytro;
- Khalil, Bilal;
- Liu, Feilin;
- Tsai, Chih‐Wei;
- Croft, Cara L;
- Carlomagno, Yari;
- DeTure, Michael;
- Salemi, Michelle;
- Cook, Casey;
- Phinney, Brett;
- Dickson, Dennis W.;
- Golde, Todd E;
- Petrucelli, Leonard;
- Rossoll, Wilfried
Publication type:
Article
Association of DNA methylation from the temporal cortex and cerebellum with AD‐related neuropathology and biochemistry.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.060867
By:
- Oatman, Stephanie R;
- Allen, Mariet;
- Quicksall, Zachary;
- Reddy, Joseph S.;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E.;
- Kanekiyo, Takahisa;
- Dickson, Dennis W.;
- Bu, Guojun;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Genome‐wide analysis identifies novel genetic variants and unique biological pathways associated with AD‐related proteins in the brain.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055337
By:
- Oatman, Stephanie R;
- Reddy, Joseph S.;
- Quicksall, Zachary;
- Carrasquillo, Minerva M.;
- Wang, Xue;
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Nguyen, Thuy;
- Malphrus, Kimberly G.;
- Heckman, Michael G.;
- Martens, Yuka A;
- Zhao, Na;
- DeTure, Michael;
- Murray, Melissa E;
- Kanekiyo, Takahisa;
- Dickson, Dennis W;
- Bu, Guojun;
- Allen, Mariet;
- Ertekin‐Taner, Nilufer
Publication type:
Article
Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 417, doi. 10.1002/alz.12198
By:
- Hou, Xu;
- Watzlawik, Jens O.;
- Cook, Casey;
- Liu, Chia‐Chen;
- Kang, Silvia S.;
- Lin, Wen‐Lang;
- DeTure, Michael;
- Heckman, Michael G.;
- Diehl, Nancy N.;
- Al‐Shaikh, Fadi S. Hanna;
- Walton, Ronald L.;
- Ross, Owen A.;
- Melrose, Heather L.;
- Ertekin‐Taner, Nilüfer;
- Bu, Guojun;
- Petrucelli, Leonard;
- Fryer, John D.;
- Murray, Melissa E.;
- Dickson, Dennis W.;
- Fiesel, Fabienne C.
Publication type:
Article
Investigating gene expression changes underlying selective hippocampal vulnerability in Alzheimer's disease using a translational neuropathology approach: Human neuropathology/selective vulnerability.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041199
By:
- Crist, Angela M.;
- Hinkle, Kelly M.;
- Wang, Xue;
- Lesser, Elizabeth R.;
- Azu, Nkem O.;
- Moloney, Christina M.;
- Frankenhauser, Isabelle;
- Labuzan, Sydney A.;
- Matchett, Billie J.;
- Liesinger, Amanda M.;
- Serie, Daniel;
- DeTure, Michael;
- Cook, Casey;
- Petrucelli, Leonard;
- Petersen, Ronald C.;
- Duara, Ranjan;
- Graff‐Radford, Neill R.;
- Allen, Mariet;
- Carrasquillo, Minerva M.;
- Li, Hu
Publication type:
Article
Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 10, p. 1372, doi. 10.1002/alz.12104
By:
- Liu, Chia‐Chen;
- Yamazaki, Yu;
- Heckman, Michael G.;
- Martens, Yuka A.;
- Jia, Lin;
- Yamazaki, Akari;
- Diehl, Nancy N.;
- Zhao, Jing;
- Zhao, Na;
- DeTure, Michael;
- Davis, Mary D.;
- Felton, Lindsey M.;
- Qiao, Wenhui;
- Li, Yonghe;
- Li, Hongmei;
- Fu, Yuan;
- Wang, Na;
- Wren, Melissa;
- Aikawa, Tomonori;
- Holm, Marie‐Louise
Publication type:
Article
Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22399-3
By:
- Crist, Angela M.;
- Hinkle, Kelly M.;
- Wang, Xue;
- Moloney, Christina M.;
- Matchett, Billie J.;
- Labuzan, Sydney A.;
- Frankenhauser, Isabelle;
- Azu, Nkem O.;
- Liesinger, Amanda M.;
- Lesser, Elizabeth R.;
- Serie, Daniel J.;
- Quicksall, Zachary S.;
- Patel, Tulsi A.;
- Carnwath, Troy P.;
- DeTure, Michael;
- Tang, Xiaojia;
- Petersen, Ronald C.;
- Duara, Ranjan;
- Graff-Radford, Neill R.;
- Allen, Mariet
Publication type:
Article
GENETIC MUTATIONS IN MAPT AND SIGNIFICANT VARIABILITY IN TAU PROTEIN MODIFICATIONS INDICATE THE EXISTANCE OF A WIDE ARRAY OF STRAINS WITHIN AND ACROSS PRIMARY AND SECONDARY TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1298, doi. 10.1016/j.jalz.2017.06.1972
By:
- DeTure, Michael;
- Tacik, Pawel;
- Kouri, Naomi;
- Carlomagno, Yari;
- Ross, Kelly;
- Murray, Melissa E.;
- Dickson, Dennis W.
Publication type:
Article
The involvement of the 5lipoxygenase pathway in tauopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P184, doi. 10.1016/j.jalz.2015.07.157
By:
- Pratico, Domenico;
- Giannopoulos, Phillip;
- Li, Jian-Guo;
- Deture, Michael;
- Dickson, Dennis
Publication type:
Article
TDP-43 filament assembly is inhibited by heat shock proteins.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P627, doi. 10.1016/j.jalz.2014.05.1091
By:
- DeTure, Michael;
- Carlomagno, Yari;
- Zhang, Yongjie;
- Davis, Mary;
- Lin, Wenlang;
- Petrucelli, Leonard
Publication type:
Article
Regulation of the Hsp90 chaperone complex by HDAC6
Published in:
2010
By:
- Cook, Casey N.;
- Dunmore, Judy;
- Gendron, Tania;
- Deture, Michael;
- Petrucelli, Leonard
Publication type:
Abstract
Characteristics of cytosolic hyperphosphorylated tau species in rTg4510 mouse brain
Published in:
2010
By:
- Sahara, Naruhiko;
- DeTure, Michael;
- Abdul-Shukkur, Ebrahim;
- Christensen, Søren;
- Kang, Dongcheul;
- Knight, Josh;
- Volbracht, Christiane;
- Petrucelli, Leonard;
- Yen, Shu-Hui;
- Lewis, Jada
Publication type:
Abstract
Induction of mutant tau expression in aged rTg4510 mice does not rapidly induce tauopathy
Published in:
2009
By:
- Cannon, Ashley D.;
- DeTure, Michael;
- Knight, Joshua;
- Alosilla, Daniel;
- Dickson, Dennis W.;
- Sahara, Naruhiko;
- Volbracht, Christiane;
- Lewis, Jada
Publication type:
Abstract
Cellular models for tau filament assembly.
Published in:
Journal of Molecular Neuroscience, 2002, v. 19, n. 3, p. 309, doi. 10.1385/JMN:19:3:309
By:
- Ko, Li-wen;
- DeTure, Michael;
- Sahara, Naruhiko;
- Chihab, Rifki;
- Yen, Shu-Hui
Publication type:
Article
Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090452
By:
- Carlomagno, Yari;
- Zhang, Yongjie;
- Davis, Mary;
- Lin, Wen-Lang;
- Cook, Casey;
- Dunmore, Judy;
- Tay, William;
- Menkosky, Kyle;
- Cao, Xiangkun;
- Petrucelli, Leonard;
- DeTure, Michael
Publication type:
Article
Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments.
Published in:
PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010810
By:
- Adams, Stephanie J.;
- DeTure, Michael A.;
- McBride, Melinda;
- Dickson, Dennis W.;
- Petrucelli, Leonard
Publication type:
Article
Tau exhibits unique seeding properties in globular glial tauopathy.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0691-9
By:
- Chung, Dah-eun Chloe;
- Carlomagno, Yari;
- Cook, Casey N.;
- Jansen-West, Karen;
- Daughrity, Lillian;
- Lewis-Tuffin, Laura J.;
- Castanedes-Casey, Monica;
- DeTure, Michael;
- Dickson, Dennis W.;
- Petrucelli, Leonard
Publication type:
Article
Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0661-2
By:
- Carlomagno, Yari;
- Chung, Dah-eun Chloe;
- Yue, Mei;
- Kurti, Aishe;
- Avendano, Nicole M.;
- Castanedes-Casey, Monica;
- Hinkle, Kelly M.;
- Jansen-West, Karen;
- Daughrity, Lillian M.;
- Tong, Jimei;
- Phillips, Virginia;
- Rademakers, Rosa;
- DeTure, Michael;
- Fryer, John D.;
- Dickson, Dennis W.;
- Petrucelli, Leonard;
- Cook, Casey
Publication type:
Article
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2024, v. 12, p. 1, doi. 10.1186/s40478-024-01731-0
By:
- Raulin, Ana-Caroline;
- Doss, Sydney V.;
- Heckman, Michael G.;
- Craver, Emily C.;
- Li, Zonghua;
- Ikezu, Tadafumi C.;
- Sekiya, Hiroaki;
- Liu, Chia-Chen;
- Martens, Yuka A.;
- Rosenberg, Cassandra L.;
- Kuchenbecker, Lindsey A.;
- DeTure, Michael;
- Reichard, R. Ross;
- Nguyen, Aivi T.;
- Constantopoulos, Eleni;
- Larsen, Rachel A.;
- Kounaves, Emmaline K.;
- Murray, Melissa E.;
- Dickson, Dennis W.;
- Petersen, Ronald C.
Publication type:
Article
Letter to the editor on: Hornerin deposits in neuronal intranuclear inclusion disease: direct identification of proteins with compositionally biased regions in inclusions by Park et al. (2022).
Published in:
Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-023-01706-7
By:
- Luo, Huihui;
- Gustavsson, Emil K.;
- Macpherson, Hannah;
- Dominik, Natalia;
- Zhelcheska, Kristina;
- Montgomery, Kylie;
- Anderson, Claire;
- Yau, Wai Yan;
- Efthymiou, Stephanie;
- Turner, Chris;
- DeTure, Michael;
- Dickson, Dennis W.;
- Josephs, Keith A.;
- Revesz, Tamas;
- Lashley, Tammaryn;
- Halliday, Glenda;
- Rowe, Dominic B.;
- McCann, Emily;
- Blair, Ian;
- Lees, Andrew J.
Publication type:
Article
Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology.
Published in:
JAMA Neurology, 2019, v. 76, n. 6, p. 710, doi. 10.1001/jamaneurol.2019.0250
By:
- Heckman, Michael G.;
- Brennan, Rebecca R.;
- Labbé, Catherine;
- Soto, Alexandra I.;
- Koga, Shunsuke;
- DeTure, Michael A.;
- Murray, Melissa E.;
- Petersen, Ronald C.;
- Boeve, Bradley F.;
- van Gerpen, Jay A.;
- Uitti, Ryan J.;
- Wszolek, Zbigniew K.;
- Rademakers, Rosa;
- Dickson, Dennis W.;
- Ross, Owen A.
Publication type:
Article
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
Published in:
2020
By:
- Prudencio, Mercedes;
- Humphrey, Jack;
- Pickles, Sarah;
- Brown, Anna-Leigh;
- Hill, Sarah E.;
- Kachergus, Jennifer M.;
- Shi, J.;
- Heckman, Michael G.;
- Spiegel, Matthew R.;
- Cook, Casey;
- Yuping Song;
- Mei Yue;
- Daughrity, Lillian M.;
- Carlomagno, Yari;
- Jansen-West, Karen;
- de Castro, Cristhoper Fernandez;
- DeTure, Michael;
- Koga, Shunsuke;
- Ying-Chih Wang;
- Sivakumar, Prasanth
Publication type:
journal article
Neuronal intranuclear inclusion disease is genetically heterogeneous.
Published in:
Annals of Clinical & Translational Neurology, 2020, v. 7, n. 9, p. 1716, doi. 10.1002/acn3.51151
By:
- Chen, Zhongbo;
- Yan Yau, Wai;
- Jaunmuktane, Zane;
- Tucci, Arianna;
- Sivakumar, Prasanth;
- Gagliano Taliun, Sarah A.;
- Turner, Chris;
- Efthymiou, Stephanie;
- Ibáñez, Kristina;
- Sullivan, Roisin;
- Bibi, Farah;
- Athanasiou‐Fragkouli, Alkyoni;
- Bourinaris, Thomas;
- Zhang, David;
- Revesz, Tamas;
- Lashley, Tammaryn;
- DeTure, Michael;
- Dickson, Dennis W.;
- Josephs, Keith A.;
- Gelpi, Ellen
Publication type:
Article
Structural insights into Alzheimer filament assembly pathways based on site-directed mutagenesis and S-glutathionylation of three-repeat neuronal Tau protein.
Published in:
Microscopy Research & Technique, 2005, v. 67, n. 3/4, p. 156, doi. 10.1002/jemt.20195
By:
- Dinoto, Luca;
- Deture, Michael A.;
- Purich, Daniel L.
Publication type:
Article
FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.
Published in:
Brain Pathology, 2017, v. 27, n. 5, p. 612, doi. 10.1111/bpa.12428
By:
- Tacik, Pawel;
- DeTure, Michael A.;
- Carlomagno, Yari;
- Lin, Wen‐Lang;
- Murray, Melissa E.;
- Baker, Matthew C.;
- Josephs, Keith A.;
- Boeve, Bradley F.;
- Wszolek, Zbigniew K.;
- Graff‐Radford, Neill R.;
- Parisi, Joseph E.;
- Petrucelli, Leonard;
- Rademakers, Rosa;
- Isaacson, Richard S.;
- Heilman, Kenneth M.;
- Petersen, Ronald C.;
- Dickson, Dennis W.;
- Kouri, Naomi
Publication type:
Article
Fibrillogenesis of Tau: Insights from Tau Missense Mutations in FTDP-17.
Published in:
Brain Pathology, 1999, v. 9, n. 4, p. 695, doi. 10.1111/j.1750-3639.1999.tb00551.x
By:
- Yen, Shu-Hui;
- Hutton, Michael;
- DeTure, Michael;
- Ko, Li-Wen;
- Nacharaju, Parimala
Publication type:
Article
APOE2 Exacerbates TDP‐43 Related Toxicity in the Absence of Alzheimer Pathology.
Published in:
Annals of Neurology, 2023, v. 93, n. 4, p. 830, doi. 10.1002/ana.26580
By:
- Meneses, Axel D.;
- Koga, Shunsuke;
- Li, Zonghua;
- O'Leary, Justin;
- Li, Fuyao;
- Chen, Kai;
- Murakami, Aya;
- Qiao, Wenhui;
- Kurti, Aishe;
- Heckman, Michael G.;
- White, Launia;
- Xie, Manling;
- Chen, Yixing;
- Finch, Nicole A.;
- Lim, Melina J.;
- Delenclos, Marion;
- DeTure, Michael A.;
- Linares, Cynthia;
- Martin, Nicholas B.;
- Ikezu, Tadafumi C.
Publication type:
Article
Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 17, p. 3421, doi. 10.1093/hmg/ddx233
By:
- Prudencio, Mercedes;
- Gonzales, Patrick K.;
- Cook, Casey N.;
- Gendron, Tania F.;
- Daughrity, Lillian M.;
- Song, Yuping;
- Ebbert, Mark T. W.;
- van Blitterswijk, Marka;
- Zhang, Yong-Jie;
- Jansen-West, Karen;
- Baker, Matthew C.;
- DeTure, Michael;
- Rademakers, Rosa;
- Boylan, Kevin B.;
- Dickson, Dennis W.;
- Petrucelli, Leonard;
- Link, Christopher D.
Publication type:
Article
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 1, p. 104, doi. 10.1093/hmg/ddt402
By:
- Cook, Casey;
- Carlomagno, Yari;
- Gendron, Tania F.;
- Dunmore, Judy;
- Scheffel, Kristyn;
- Stetler, Caroline;
- Davis, Mary;
- Dickson, Dennis;
- Jarpe, Matthew;
- DeTure, Michael;
- Petrucelli, Leonard
Publication type:
Article
Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 13, p. 2936, doi. 10.1093/hmg/dds125
By:
- Cook, Casey;
- Gendron, Tania F.;
- Scheffel, Kristyn;
- Carlomagno, Yari;
- Dunmore, Judy;
- DeTure, Michael;
- Petrucelli, Leonard
Publication type:
Article
Frequency of Comorbid Pathologies and Their Clinical Impact in Multiple System Atrophy.
Published in:
Movement Disorders, 2024, v. 39, n. 2, p. 380, doi. 10.1002/mds.29670
By:
- Sekiya, Hiroaki;
- Koga, Shunsuke;
- Murakami, Aya;
- DeTure, Michael;
- Ross, Owen A.;
- Uitti, Ryan J.;
- Cheshire, William P.;
- Wszolek, Zbigniew K.;
- Dickson, Dennis W.
Publication type:
Article
Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups.
Published in:
Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02778-y
By:
- Ma, Yiyi;
- Reyes-Dumeyer, Dolly;
- Piriz, Angel;
- Recio, Patricia;
- Mejia, Diones Rivera;
- Medrano, Martin;
- Lantigua, Rafael A.;
- Vonsattel, Jean Paul G.;
- Tosto, Giuseppe;
- Teich, Andrew F.;
- Ciener, Benjamin;
- Leskinen, Sandra;
- Sivakumar, Sharanya;
- DeTure, Michael;
- Ranjan, Duara;
- Dickson, Dennis;
- Murray, Melissa;
- Lee, Edward;
- Wolk, David A.;
- Jin, Lee-Way
Publication type:
Article
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Published in:
Acta Neuropathologica, 2022, v. 143, n. 6, p. 641, doi. 10.1007/s00401-022-02421-8
By:
- Jin, Yunjung;
- Li, Fuyao;
- Sonoustoun, Berkiye;
- Kondru, Naveen Chandra;
- Martens, Yuka A.;
- Qiao, Wenhui;
- Heckman, Michael G.;
- Ikezu, Tadafumi C.;
- Li, Zonghua;
- Burgess, Jeremy D.;
- Amerna, Danilyn;
- O'Leary, Justin;
- DeTure, Michael A.;
- Zhao, Jing;
- McLean, Pamela J.;
- Dickson, Dennis W.;
- Ross, Owen A.;
- Bu, Guojun;
- Zhao, Na
Publication type:
Article

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