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- Title
Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study.
- Authors
Bhurat, Rishab; Premkumar, Sarala; Manokaran, Ranjith Kumar
- Abstract
Objective: To study the association between serum magnesium level and migraine in children. Methods: This cross-sectional study enrolled children aged 5–18 years diagnosed with migraine, and age- and sex-matched controls without a headache disorder. International Classification of Headache Disorders 3 (ICHD-3) was used for the diagnosis of migraine. The association between serum magnesium level and migraine headache was analyzed. Results: A total of 35 children with migraine were enrolled with 35 control subjects. The median (IQR) serum magnesium levels were comparable among children with migraine and controls [2.0 (2.0,2.1) vs 2.2 (1.9, 2.2) mg/dL; P=0.23], respectively. In adolescent subgroup, median (IQR) serum magnesium levels were significantly low among the children with migraine as compared to those without migraine [2.0 (1.9, 2.1) vs 2.2 (2.0, 2.2 mg/dL); P<0.045]. Conclusion: We found a statistically significant association between low serum magnesium levels and the occurrence of migraine in adolescents, which may have treatment implications.
- Subjects
MIGRAINE; MAGNESIUM; CROSS-sectional method; HEADACHE
- Publication
Indian Pediatrics, 2022, Vol 59, Issue 8, p623
- ISSN
0019-6061
- Publication type
Article
- DOI
10.1007/s13312-022-2576-4