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- Title
Structure–function analysis for macular surgery in patients with coexisting glaucoma.
- Authors
Yu, Sarah N.; Hood, Donald C.; Blumberg, Dana M.; Chang, Stanley; Greenstein, Vivienne C.
- Abstract
Purpose: To develop methods to assess the effects of epiretinal membranes (ERM) and macular holes (MH) coexisting with glaucoma on pre-operative retinal structure and function and evaluate post-operative outcomes. Methods: Seven eyes of 7 patients with glaucoma, 6 with ERMs and 1 with MH, were enrolled; 4 underwent vitrectomy for ERM and one for MH. Visual fields (VFs) and optical coherence tomography (OCT) scans were obtained pre- and post-operatively. The 10-2VF deviation map was overlayed on ganglion cell and inner plexiform layer (GCL + IPL) and retinal nerve fiber layer (RNFL) deviation maps derived from OCT macula and disc cube scans. Optic nerve circle scans were obtained to assess RNFL thickness, and OCT b-scans associated with VF defects were compared pre- and post-operatively. Results: Examination of pre-operative VFs and OCT scans showed the importance of determining the extent to which glaucomatous damage contributed to VF loss; verifying automated segmentation of the GCL + IPL and RNFL; and assessing foveal anatomy. Evaluation of post-operative structure–function outcomes required correction of magnification changes in OCT scans and repeated follow-up visits to clarify the origin of VF changes. Conclusions: Pre-operative comparisons of VFs and OCT scans may be beneficial in guiding surgical planning, and evaluating outcomes, in eyes with glaucoma undergoing macular surgery.
- Subjects
OPTICAL coherence tomography; GLAUCOMA; TRABECULECTOMY; VISUAL fields; OPHTHALMIC surgery; OPTIC nerve; NERVE fibers
- Publication
Graefe's Archive of Clinical & Experimental Ophthalmology, 2022, Vol 260, Issue 5, p1475
- ISSN
0721-832X
- Publication type
Article
- DOI
10.1007/s00417-021-05481-w