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- Title
天然冰片开放血-脑屏障及潜在抑制肿瘤作用机制的研究进展.
- Authors
滕振飞; 朱磊; 张恒柱; 魏民; 王杏东; 刘晓光; 李育平
- Abstract
With the development of the industrial level, the generation of modern means of transportation and the prominent environmental problems, the incidence of brain trauma and brain tumors is gradually increasing. These brain diseases are called critical because of their high disability and mortality disease. Research on the treatment of such diseases has always been a thorny issue in the pharmaceutical industry. Since many drugs cannot pass through the blood-brain barrier or not sufficient to control the disease, drugs that can be used to treat intracranial diseases are relatively limited. Borneol is a kind of aromaatic traditional Chinese medicine, which is called “adjuvant drug”. It has strong liposoluble, easy to penetrate and open the blood-brain barrier, and can increase the permeability of other drugs to achieve better therapeutic efficacy. In addition, borneol can regulate the blood vessels by changing the content of neurotransmitters in the body, and has a certain degree of brain protection and potential inhibition of tumor growth. This has important theoretical significance and application value for the treatment of intracranial lesions.
- Publication
Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi, 2021, Vol 18, Issue 5, p597
- ISSN
1672-7770
- Publication type
Article
- DOI
10.3969/j.issn.1672-7770.2021.05.025