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- Title
Association Between Mobilization and Composite Postoperative Complications Following Major Elective Surgery.
- Authors
Turan, Alparslan; Khanna, Ashish K.; Brooker, Jack; Saha, Amit K.; Clark, Clancy J.; Samant, Anusha; Ozcimen, Elif; Pu, Xuan; Ruetzler, Kurt; Sessler, Daniel I.
- Abstract
Key Points: Question: What is the association between postoperative mobilization and a composite of postoperative outcomes, cumulative postoperative pain, and 30-day readmission risk in patients after major elective surgery? Findings: In this cohort study of 8653 patients who underwent major elective surgery, every 4 minutes of mobilization per monitored hour was inversely associated with the composite of postoperative complications and with shorter hospital length of stay. Meaning: The findings indicate that mobilization was associated with a lower hazard for postoperative complications and shorter hospitalization. This cohort study evaluates the association between mobilization and a collapsed composite of complications after major elective surgery. Importance: Mobilization after surgery is a key component of Enhanced Recovery after Surgery (ERAS) pathways. Objective: To evaluate the association between mobilization and a collapsed composite of postoperative complications in patients recovering from major elective surgery as well as hospital length of stay, cumulative pain scores, and 30-day readmission rates. Design, Setting, and Participants: This retrospective observational study conducted at a single quaternary US referral center included patients who had elective surgery between February 2017 and October 2020. Mobilization was assessed over the first 48 postoperative hours with wearable accelerometers, and outcomes were assessed throughout hospitalization. Patients who had elective surgery lasting at least 2 hours followed by at least 48 hours of hospitalization were included. A minimum of 12 hours of continuous accelerometer monitoring was required without missing confounding variables or key data. Among 16 203 potential participants, 8653 who met inclusion criteria were included in the final analysis. Data were analyzed from February 2017 to October 2020. Exposures: Amount of mobilization per hour for 48 postoperative hours. Outcomes: The primary outcome was a composite of myocardial injury, ileus, stroke, venous thromboembolism, pulmonary complications, and all-cause in-hospital mortality. Secondary outcomes included hospital length of stay, cumulative pain scores, and 30-day readmission. Results: Of 8653 included patients (mean [SD] age, 57.6 [16.0] years; 4535 [52.4%] female), 633 (7.3%) experienced the primary outcome. Mobilization time was a median (IQR) of 3.9 (1.7-7.8) minutes per monitored hour overall, 3.2 (0.9-7.4) in patients who experienced the primary outcome, and 4.1 (1.8-7.9) in those who did not. There was a significant association between postoperative mobilization and the composite outcome (hazard ratio [HR], 0.75; 95% CI, 0.67-0.84; P <.001) for each 4-minute increase in mobilization. Mobilization was associated with an estimated median reduction in the duration of hospitalization by 0.12 days (95% CI, 0.09-0.15; P <.001) for each 4-minute increase in mobilization. The were no associations between mobilization and pain score or 30-day readmission. Conclusions and Relevance: In this study, mobilization measured by wearable accelerometers was associated with fewer postoperative complications and shorter hospital length of stay.
- Publication
JAMA Surgery, 2023, Vol 158, Issue 8, p825
- ISSN
2168-6254
- Publication type
Article
- DOI
10.1001/jamasurg.2023.1122