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- Title
Organ-Specific Positron Emission Tomography Scanners for Breast Imaging: Comparison between the Performances of Prior and Novel Models.
- Authors
Satoh, Yoko; Hanaoka, Kohei; Ikegawa, Chihiro; Imai, Masamichi; Watanabe, Shota; Morimoto-Ishikawa, Daisuke; Onishi, Hiroshi; Ito, Toshikazu; Komoike, Yoshifumi; Ishii, Kazunari
- Abstract
The performances of photomultiplier tube (PMT)-based dedicated breast positron emission tomography (PET) and silicon photomultiplier tube (SiPM)-based time-of-flight (TOF) PET, which is applicable not only to breast imaging but also to head imaging, were compared using a phantom study. A cylindrical phantom containing four spheres (3–10 mm in diameter) filled with 18F-FDG at two signal-to-background ratios (SBRs), 4:1 and 8:1, was scanned. The phantom images, which were reconstructed using three-dimensional list-mode dynamic row-action maximum likelihood algorithm with various β-values and post-smoothing filters, were visually and quantitatively compared. Visual evaluation showed that the 3 mm sphere was more clearly visualized with higher β and smaller post-filters, while the background was noisier; SiPM-based TOF-PET was superior to PMT-based dbPET in sharpness, smoothness, and detectability, although the background was noisier at the SBR of 8:1. Quantitative evaluation revealed that the detection index (DI) and recovery coefficient (CRC) of SiPM-based TOF-PET images were higher than those of PMT-based PET images, despite a higher background coefficient of variation (CVBG). The two organ-specific PET systems showed that a 3 mm lesion in the breast could be visualized at the center of the detector, and there was less noise in the SiPM-based TOF-PET image.
- Subjects
POSITRON emission tomography; BREAST imaging; OPTICAL scanners; PHOTOMULTIPLIERS
- Publication
Diagnostics (2075-4418), 2023, Vol 13, Issue 6, p1079
- ISSN
2075-4418
- Publication type
Article
- DOI
10.3390/diagnostics13061079