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Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes.
Published in:
Molecular Medicine, 2019, v. 25, n. 1, p. N.PAG, doi. 10.1186/s10020-019-0084-3
By:
- Mirea, Andreea-Manuela;
- Toonen, Erik J. M.;
- van den Munckhof, Inge;
- Munsterman, Isabelle D.;
- Tjwa, Eric T. T. L.;
- Jaeger, Martin;
- Oosting, Marije;
- Schraa, Kiki;
- Rutten, Joost H. W.;
- van der Graaf, Marinette;
- Riksen, Niels P.;
- de Graaf, Jacqueline;
- Netea, Mihai G.;
- Tack, Cees J.;
- Chavakis, Triantafyllos;
- Joosten, Leo A. B.
Publication type:
Article
Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes.
Published in:
Molecular Medicine, 2019, v. 25, n. 1, p. 1, doi. 10.1186/s10020-019-0084-3
By:
- Mirea, Andreea-Manuela;
- Toonen, Erik J. M.;
- van den Munckhof, Inge;
- Munsterman, Isabelle D.;
- Tjwa, Eric T. T. L.;
- Jaeger, Martin;
- Oosting, Marije;
- Schraa, Kiki;
- Rutten, Joost H. W.;
- van der Graaf, Marinette;
- Riksen, Niels P.;
- de Graaf, Jacqueline;
- Netea, Mihai G.;
- Tack, Cees J.;
- Chavakis, Triantafyllos;
- Joosten, Leo A. B.
Publication type:
Article
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1039765
By:
- Hurler, Lisa;
- Toonen, Erik J. M.;
- Kajdácsi, Erika;
- van Bree, Bregje;
- Brandwijk, Ricardo J. M. G. E.;
- de Bruin, Wieke;
- Lyons, Paul A.;
- Bergamaschi, Laura
Publication type:
Article
Pitfalls in complement analysis: A systematic literature review of assessing complement activation.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.1007102
By:
- Brandwijk, Ricardo J. M. G. E.;
- Michels, Marloes A. H. M.;
- van Rossum, Mara;
- de Nooijer, Aline H.;
- Nilsson, Per H.;
- de Bruin, Wieke C. C.;
- Toonen, Erik J. M.
Publication type:
Article
Corrigendum: A Family Affair: Addressing the Challenges of Factor H and the Related Proteins.
Published in:
2022
By:
- Poppelaars, Felix;
- Goicoechea de Jorge, Elena;
- Jongerius, Ilse;
- Baeumner, Antje J.;
- Steiner, Mark-Steven;
- Józsi, Mihály;
- Toonen, Erik J. M.;
- Pauly, Diana
Publication type:
Correction Notice
Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining.
Published in:
BioData Mining, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-0381-6-2
By:
- Fleuren, Wilco W. M.;
- Toonen, Erik J. M.;
- Verhoeven, Stefan;
- Frijters, Raoul;
- Hulsen, Tim;
- Rullmann, Ton;
- van Schaik, René;
- de Vlieg, Jacob;
- Alkema, Wynand
Publication type:
Article
Glucose Kinetics in the Collagen-Induced Arthritis Model: An All-in-One Model to Assess Both Efficacy and Metabolic Side Effects of Glucocorticoids.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0098684
By:
- Toonen, Erik J. M.;
- Laskewitz, Anke J.;
- van Dijk, Theo H.;
- Bleeker, Aycha;
- Grefhorst, Aldo;
- Schouten, Annelies E.;
- Bastiaanssen, Ellen A. J.;
- Ballak, Dov B.;
- Koenders, Marije I.;
- van Doorn, Cindy;
- van der Vleuten, Monique A. J.;
- van Lierop, Marie-Jose C.;
- Groen, Albert K.;
- Dokter, Wim H. A.
Publication type:
Article
Validation Study of Existing Gene Expression Signatures for Anti-TNF Treatment in Patients with Rheumatoid Arthritis.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033199
By:
- Toonen, Erik J. M.;
- Gilissen, Christian;
- Franke, Barbara;
- Kievit, Wietske;
- Eijsbouts, Agnes M.;
- Broeder, Alfons A. den;
- van Reijmersdal, Simon V.;
- Veltman, Joris A.;
- Scheffer, Hans;
- Radstake, Timothy R. D. J.;
- van Riel, Piet L. C. M.;
- Barrera, Pilar;
- Coenen, Marieke J. H.
Publication type:
Article
Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014326
By:
- Coenen, Marieke J. H.;
- Enevold, Christian;
- Barrera, Pilar;
- Schijvenaars, Mascha M. V. A. P.;
- Toonen, Erik J. M.;
- Scheffer, Hans;
- Padyukov, Leonid;
- Kastbom, Alf;
- Klareskog, Lars;
- Barton, Anne;
- Kievit, Wietske;
- Rood, Maarten J.;
- Jansen, Tim L.;
- Swinkels, Dorine;
- Riel, Piet L. C. M. van;
- Franke, Barbara;
- Bendtzen, Klaus;
- Radstake, Timothy R. D. J.
Publication type:
Article
Complement C7 and clusterin form a complex in circulation.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1330095
By:
- Massri, Mariam;
- Toonen, Erik J. M.;
- Sarg, Bettina;
- Kremser, Leopold;
- Grasse, Marco;
- Fleischer, Verena;
- Torres-Quesada, Omar;
- Hengst, Ludger;
- Skjoedt, Mikkel-Ole;
- Bayarri-Olmos, Rafael;
- Rosbjerg, Anne;
- Garred, Peter;
- Orth-Höller, Dorothea;
- Prohászka, Zolta'n;
- Würzner, Reinhard
Publication type:
Article
Editorial: Current challenges in complement diagnostics.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1334050
By:
- Nilsson, Per H.;
- Skattum, Lillemor;
- Toonen, Erik J. M.
Publication type:
Article
Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2012, v. 14, n. 6, p. 1, doi. 10.1186/ar4110
By:
- Toonen, Erik J. M.;
- Barrera, Pilar;
- Fransen, Jaap;
- de Brouwer, Arjan P.M.;
- Eijsbouts, Agnes M.;
- Miossec, Pierre;
- Marotte, Hubert;
- Scheffer, Hans;
- van Riel, Piet L.C.M;
- Franke, Barbara;
- Coenen, Marieke J. H.
Publication type:
Article
A Family Affair: Addressing the Challenges of Factor H and the Related Proteins.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.660194
By:
- Poppelaars, Felix;
- Goicoechea de Jorge, Elena;
- Jongerius, Ilse;
- Baeumner, Antje J.;
- Steiner, Mark-Steven;
- Józsi, Mihály;
- Toonen, Erik J. M.;
- Pauly, Diana
Publication type:
Article
Differentiating between activation via the lectin or the classical complement pathway in patients with systemic lupus erythematosus.
Published in:
Clinical & Experimental Immunology, 2023, v. 214, n. 1, p. 18, doi. 10.1093/cei/uxad070
By:
- Larsen, Mads Lamm;
- Troldborg, Anne;
- Toonen, Erik J M;
- Hurler, Lisa;
- Prohaszka, Zoltan;
- Cervenak, László;
- Gudmann Hansen, Annette;
- Thiel, Steffen
Publication type:
Article
Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity.
Published in:
Critical Care, 2023, v. 27, n. 1, p. 1, doi. 10.1186/s13054-023-04344-6
By:
- de Nooijer, Aline H.;
- Kotsaki, Antigone;
- Kranidioti, Eleftheria;
- Kox, Matthijs;
- Pickkers, Peter;
- Toonen, Erik J. M.;
- Giamarellos-Bourboulis, Evangelos J.;
- Netea, Mihai G.
Publication type:
Article
Frailty is related to serum inflammageing markers: results from the VITAL study.
Published in:
Immunity & Ageing, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12979-023-00391-3
By:
- van Sleen, Yannick;
- Shetty, Sudarshan A.;
- van der Heiden, Marieke;
- Venema, Milou C. A.;
- Gutiérrez-Melo, Nicolas;
- Toonen, Erik J. M.;
- van Beek, Josine;
- Buisman, Anne-Marie;
- van Baarle, Debbie;
- Sauce, Delphine
Publication type:
Article
Oxidative Stress Increases Endogenous Complement-Dependent Inflammatory and Angiogenic Responses in Retinal Pigment Epithelial Cells Independently of Exogenous Complement Sources.
Published in:
Antioxidants, 2019, v. 8, n. 11, p. 548, doi. 10.3390/antiox8110548
By:
- Trakkides, Timon-Orest;
- Schäfer, Nicole;
- Reichenthaler, Maria;
- Kühn, Konstanze;
- Brandwijk, Ricardo J. M. G. E.;
- Toonen, Erik J. M.;
- Urban, Florian;
- Wegener, Joachim;
- Enzmann, Volker;
- Pauly, Diana
Publication type:
Article
Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance.
Published in:
Molecular Medicine, 2016, v. 22, n. 1, p. 202, doi. 10.2119/molmed.2016.00033
By:
- Toonen, Erik J M;
- Mirea, Andreea-Manuela;
- Tack, Cees J;
- Stienstra, Rinke;
- Ballak, Dov B;
- van Diepen, Janna A;
- Hijmans, Anneke;
- Chavakis, Triantafyllos;
- Dokter, Wim H;
- Pham, Christine T N;
- Netea, Mihai G;
- Dinarello, Charles A;
- Joosten, Leo A B
Publication type:
Article
Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance.
Published in:
Molecular Medicine, 2016, v. 22, p. 202, doi. 10.2119/molmed.2016.00033
By:
- Toonen, Erik J. M.;
- Mirea, Andreea-Manuela;
- Tack, Cees J.;
- Stienstra, Rinke;
- Ballak, Dov B.;
- van Diepen, Janna A.;
- Hijmans, Anneke;
- Chavakis, Triantafyllos;
- Dokter, Wim H.;
- Pham, Christine T. N.;
- Netea, Mihai G.;
- Dinarello, Charles A.;
- Joosten, Leo A. B.
Publication type:
Article
Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes.
Published in:
2021
By:
- Nooijer, Aline H de;
- Grondman, Inge;
- Janssen, Nico A F;
- Netea, Mihai G;
- Willems, Loek;
- Veerdonk, Frank L van de;
- Giamarellos-Bourboulis, Evangelos J;
- Toonen, Erik J M;
- Joosten, Leo A B;
- group, RCI-COVID-19 study;
- de Nooijer, Aline H;
- van de Veerdonk, Frank L;
- RCI-COVID-19 study group
Publication type:
journal article
Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1091, doi. 10.3390/ijms25021091
By:
- Andersson, Linnea I.;
- Sjöström, Dick J.;
- Quach, Huy Quang;
- Hägerström, Kim;
- Hurler, Lisa;
- Kajdácsi, Erika;
- Cervenak, László;
- Prohászka, Zoltán;
- Toonen, Erik J. M.;
- Mohlin, Camilla;
- Mollnes, Tom Eirik;
- Sandgren, Per;
- Tjernberg, Ivar;
- Nilsson, Per H.
Publication type:
Article
Autoantibody Profiling and Anti-Kinesin Reactivity in ANCA-Associated Vasculitis.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15341, doi. 10.3390/ijms242015341
By:
- Mescia, Federica;
- Bayati, Shaghayegh;
- Brouwer, Elisabeth;
- Heeringa, Peter;
- Toonen, Erik J. M.;
- Beenes, Marijke;
- Ball, Miriam J.;
- Rees, Andrew J.;
- Kain, Renate;
- Lyons, Paul A.;
- Nilsson, Peter;
- Pin, Elisa
Publication type:
Article
Prednisolone-induced differential gene expressionin mouse liver carrying wild type or adimerization-defective glucocorticoid receptor.
Published in:
BMC Genomics, 2010, v. 11, p. 359, doi. 10.1186/1471-2164-11-359
By:
- Frijters, Raoul;
- Fleuren, Wilco;
- Toonen, Erik J. M.;
- Tuckermann, Jan P.;
- Reichardt, Holger M.;
- van der Maaden, Hans;
- van Elsas, Andrea;
- van Lierop, Marie-Jose;
- Dokter, Wim;
- de Vlieg, Jacob;
- Alkema, Wynand
Publication type:
Article
Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19761-2
By:
- Buckland, Matthew S.;
- Galloway, James B.;
- Fhogartaigh, Caoimhe Nic;
- Meredith, Luke;
- Provine, Nicholas M.;
- Bloor, Stuart;
- Ogbe, Ane;
- Zelek, Wioleta M.;
- Smielewska, Anna;
- Yakovleva, Anna;
- Mann, Tiffeney;
- Bergamaschi, Laura;
- Turner, Lorinda;
- Mescia, Frederica;
- Toonen, Erik J. M.;
- Hackstein, Carl-Philipp;
- Akther, Hossain Delowar;
- Vieira, Vinicius Adriano;
- Ceron-Gutierrez, Lourdes;
- Periselneris, Jimstan
Publication type:
Article
Angiopoietin-2/-1 ratios and MMP-3 levels as an early warning sign for the presence of giant cell arteritis in patients with polymyalgia rheumatica.
Published in:
Arthritis Research & Therapy, 2022, v. 24, n. 1, p. 1, doi. 10.1186/s13075-022-02754-5
By:
- van Sleen, Yannick;
- Therkildsen, Philip;
- Nielsen, Berit Dalsgaard;
- van der Geest, Kornelis S. M.;
- Hansen, Ib;
- Heeringa, Peter;
- Posthumus, Marcel D.;
- Sandovici, Maria;
- Toonen, Erik J. M.;
- Zijlstra, Jannik;
- Boots, Annemieke M. H.;
- Hauge, Ellen-Margrethe;
- Brouwer, Elisabeth
Publication type:
Article

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