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- Title
Oral topical cidofovir: novel route of drug delivery in a severely immunosuppressed patient with refractory multidrug-resistant herpes simplex virus infection.
- Authors
Sims, C. R.; Thompson, K.; Chemaly, R. F.; Shpall, E. J.; Champlin, R. E.; Safdar, A.
- Abstract
We present a case of serious treatment-refractory acyclovir- and foscarnet-resistant herpes simplex virus (HSV) type-1 orolingual infection that responded to oral cidofovir rinses after failure of acyclovir and foscarnet therapy. The use of 3% cidofovir in a saline rinse for refractory mucosal HSV infection appears promising but needs prospective evaluation.
- Subjects
HERPES simplex virus; HERPESVIRUSES; ACYCLOVIR; ANTIMETABOLITES; DISEASE complications; NUCLEOSIDES
- Publication
Transplant Infectious Disease, 2007, Vol 9, Issue 3, p256
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/j.1399-3062.2007.00261.x