We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Secondary neuroendocrine tumor after allogeneic bone marrow transplantation.
- Authors
Tamura, Shinichi; Ishida, Hiroyuki; Naito, Takeshi; Kondo, Osamu; Inoue, Masami; Kawa, Keisei; Kawabata, Kenji; Hojo, Hiroshi; Ouchi, Kazutaka; Imamura, Toshihiko
- Abstract
Here we report a case of aggressive neuroendocrine tumor (NET), which is an extremely rare secondary solid tumor that occurs after allogeneic hematopoietic cell transplantation (allo-HSCT). A patient with chronic active Epstein- Barr virus infection received allo-HSCT from an HLA-DR two allele-mismatched unrelated donor. Four years later, he developed NET with multiple metastases. He received thoraco-abdominal irradiation as a conditioning regimen, and developed repeated episodes of intestinal graft-versus-host disease, for which he received long-term immunosuppressive therapy. Although these factors may be potential contributing factors to the development of secondary NET, the exact pathogenesis remains unclear.
- Subjects
NEUROENDOCRINE tumors; BONE marrow transplantation; HOMOGRAFTS; DIAGNOSIS
- Publication
Pediatrics International, 2015, Vol 57, Issue 6, p1178
- ISSN
1328-8067
- Publication type
Article
- DOI
10.1111/ped.12720