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- Title
The Combination of Solid-State Chemistry and Medicinal Chemistry as the Basis for the Synthesis of Theranostics Platforms.
- Authors
Korolev, Dmitry; Postnov, Viktor; Aleksandrov, Ilia; Murin, Igor
- Abstract
This review presents the main patterns of synthesis for theranostics platforms. We examine various approaches to the interpretation of theranostics, statistics of publications drawn from the PubMed database, and the solid-state and medicinal chemistry methods used for the formation of nanotheranostic objects. We highlight and analyze chemical methods for the modification of nanoparticles, synthesis of spacers with functional end-groups, and the immobilization of medicinal substances and fluorophores. An overview of the modern solutions applied in various fields of medicine is provided, along with an outline of specific examples and an analysis of modern trends and development areas of theranostics as a part of personalized medicine.
- Subjects
PHARMACEUTICAL chemistry; COMPANION diagnostics; INDIVIDUALIZED medicine; FLUOROPHORES; TREND analysis
- Publication
Biomolecules (2218-273X), 2021, Vol 11, Issue 10, p1544
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom11101544