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- Title
The acquired immunodeficiency syndrome and Mycobacterium avium-intracellulare bacteremia in a patient with hemophilia.
- Authors
Elliott, James L.; Hoppes, William L.; Platt, Marvin S.; Thomas, John G.; Patel, Indravadan P.; Gansar, Ali; Elliott, J L; Hoppes, W L; Platt, M S; Thomas, J G; Patel, I P; Gansar, A
- Abstract
A 27-year-old previously healthy man with hemophilia presented with Pneumocystis carinii pneumonia. The patient had several episodes of oral candidiasis followed by disseminated infection with Mycobacterium avium-intracellulare. He was not homosexual nor did he take illicit drugs, but he had been self-administering two to four monthly infusions of factor VIII concentrate for 7 years. In-vitro lymphocyte studies showed findings consistent with the acquired immunodeficiency syndrome that had previously been reported only in homosexual men, drug addicts, and Haitian refugees. The cause of this syndrome is unknown, but the possibility that it is associated with a transmissible agent acquired through the use of blood products such as factor VIII concentrate must be considered.
- Subjects
HEMOPHILIA; HEMOPHILIACS; PNEUMOCYSTIS carinii; HIV infection transmission; HEMOPHILIA complications; HETEROCYCLIC compounds; PEPTIDE hormones; AIDS; CYTOMEGALOVIRUSES; EPSTEIN-Barr virus; IMMUNOGLOBULINS; LYMPHOKINES; MYCOBACTERIAL diseases; MYCOBACTERIUM avium; PNEUMOCYSTIS pneumonia; PROTOZOA; VIRAL antibodies; DISEASE complications; THERAPEUTICS
- Publication
Annals of Internal Medicine, 1983, Vol 98, Issue 3, p290
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-98-3-290