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- Title
Effects of Alexidine 2HCl Mouthwash on Plaque and Gingivitis After Six Months.
- Authors
SPOLSKY, VLADIMIR W.; FORSYTHE, ALAN B.
- Abstract
Two-hundred and fourteen subjects ranging in age from 22 to 63 years used either a mouthwash that contained 0.035% w/v alexidine 2HCl (2-ethylhexyl bisbiguanidine dihydrochloride) or a placebo twice daily on a double-blind basis for six months in conjunction with routine oral hygiene procedures. The results indicated that alexidine 2HCl was safe and was statistically more effective in producing a clinically significant reduction in gingivitis than was the placebo.
- Subjects
MOUTHWASHES; DENTAL plaque; GINGIVITIS; ORAL hygiene; CHLORIDES; DENTAL caries; PREVENTION
- Publication
Journal of Dental Research, 1977, Vol 56, Issue 11, p1349
- ISSN
0022-0345
- Publication type
Article
- DOI
10.1177/00220345770560111101