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- Title
CT imaging changes of corona virus disease 2019(COVID-19): a multi-center study in Southwest China.
- Authors
Li, Xiaoming; Zeng, Wenbing; Li, Xiang; Chen, Haonan; Shi, Linping; Li, Xinghui; Xiang, Hongnian; Cao, Yang; Chen, Hui; Liu, Chen; Wang, Jian
- Abstract
<bold>Background: </bold>Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection in southwest China.<bold>Methods: </bold>In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed.<bold>Results: </bold>A total of 100 (76%) patients had a history of close contact with people living in Wuhan, Hubei. The clinical manifestations of COVID-19 included cough, fever. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved, 20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening, hydrothorax, pericardial effusion, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes.<bold>Conclusion: </bold>Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time.
- Subjects
WUHAN (China); CHINA; COVID-19; VIRUS diseases; CHEST examination; PERICARDIAL effusion; CHEST X rays; COMPUTED tomography; CLINICAL pathology; EPIDEMICS; LUNGS; MEDICAL cooperation; RESEARCH; RESEARCH funding; RETROSPECTIVE studies; DISEASE progression
- Publication
Journal of Translational Medicine, 2020, Vol 18, Issue 1, p1
- ISSN
1479-5876
- Publication type
journal article
- DOI
10.1186/s12967-020-02324-w