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- Title
Health care workers in Pearl River Delta Area of China are not vaccinated adequately against hepatitis B: a retrospective cohort study.
- Authors
Yu-Bao Zheng; Yu-Rong Gu; Min Zhang; Ke Wang; Zhan-lian Huang; Chao-Shuang Lin; Zhi-Liang Gao; Zheng, Yu-Bao; Gu, Yu-Rong; Zhang, Min; Wang, Ke; Huang, Zhan-Lian; Lin, Chao-Shuang; Gao, Zhi-Liang
- Abstract
<bold>Backgrounds: </bold>Health-care workers' (HCWs) exposure to bodily fluids puts them at risk of hepatitis B virus HBV infection. This study investigated HBV vaccination practices and outcomes in HCWs and assessed postvaccination seroprotection across HCWs in different departments.<bold>Methods: </bold>A survey of HCWs in a Chinese public general hospital was carried out with a retrospective cohort of 1420 hospital HCWs (458 males and 962 females). HBV vaccination status (10-μg/dose used) was investigated in the cohort from vaccination records from the period of 1988 to 2008. Blood samples were collected and tested for hepatitis B surface antigen (HBsAg) and HBV antibodies (anti-HBs).<bold>Results: </bold>The overall vaccination (complete course) and HBsAg carrier rates among HCWs were 40.42 % (574/1420) and 6.13 % (87/1420), respectively. Vaccination rates differed by department, with HCWs in internal medicine (39.5 %) and emergency (42.0 %) departments having particularly low rates. The natural infection rate was 7.53 % (107/1420) among HCWs. HCWs in the department of infectious diseases (vaccination rate, 57.8 %) had the highest rate of antibody produced by natural infection (88.2 %).<bold>Conclusion: </bold>The vaccination rate was a disappointingly low among HCWs in Pearl River Delta Area of China. HCWs working in infectious diseases departments and technicians were at particularly likely to have been infected with HBV. A concerted effort is needed to bring vaccination rates up among Chinese HCWs in Pearl River Delta Area of southern China.
- Subjects
CHINA; MEDICAL personnel; VACCINATION of adults; HEPATITIS B; RETROSPECTIVE studies; COHORT analysis; BLOOD sampling; HOSPITAL personnel; HEPATITIS B prevention; CARRIER state (Communicable diseases); HEPATITIS B vaccines; HEPATITIS viruses; HOSPITALS; IMMUNIZATION; NATURE; SURVEYS; VIRAL antibodies; VIRAL antigens
- Publication
BMC Infectious Diseases, 2015, Vol 15, p1
- ISSN
1471-2334
- Publication type
journal article
- DOI
10.1186/s12879-015-1278-0