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- Title
Continuous marennin production by agar-entrapped Haslea ostrearia using a tubular photobioreactor with internal illumination.
- Authors
Lebeau, T.; Gaudin, P.; Junter, G.-A.; Mignot, L.; Robert, J.-M.
- Abstract
The marine diatom Haslea ostrearia was immobilized in a tubular agar gel layer introduced into a photobioreactor of original design with internal illumination for the continuous synthesis of marennin, a blue-green pigment of biotechnological interest. Marennin was produced for a long-term period (27–43 days) and the volumetric productivity was maximum (18.7 mg day-1 l-1 gel) at the highest dilution rate (0.25 day-1) and lowest agar layer thickness (3 mm). Heterogeneous cell distribution in the agar layer revealed diffusional limitation of light and nutrients. However, the 3 mm gel thickness led to a more homogeneous cell distribution during incubation and to an increase of the whole biomass in the agar gel layer.
- Subjects
BIOREACTORS; DIATOMS; ALGAE; BIOLOGICAL pigments; AGAR
- Publication
Applied Microbiology & Biotechnology, 2000, Vol 54, Issue 5, p634
- ISSN
0175-7598
- Publication type
Article
- DOI
10.1007/s002530000380