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Improved antibody-guided surgery with a near-infrared dye on a pegylated linker for CEA-positive tumors.
Published in:
Journal of Biomedical Optics, 2019, v. 24, n. 6, p. 66012, doi. 10.1117/1.JBO.24.6.066012
By:
- Yazaki, Paul J.;
- Lwin, Thinzar M.;
- Minnix, Megan;
- Li, Lin;
- Sherman, Anakim;
- Molnar, Justin;
- Miller, Aaron;
- Frankel, Paul;
- Chea, Junie;
- Poku, Erasmus;
- Bowles, Nicole;
- Hoffman, Robert M.;
- Shively, John E.;
- Bouvet, Michael
Publication type:
Article
Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models.
Published in:
In Vivo, 2020, v. 34, n. 5, p. 2303, doi. 10.21873/invivo.12042
By:
- HOLLANDSWORTH, HANNAH M.;
- HIROTO NISHINO;
- TURNER, MICHAEL;
- AMIRFAKHRI, SIAMAK;
- FILEMONI, FILEMONI;
- HOFFMAN, ROBERT M.;
- YAZAKI, PAUL J.;
- BOUVET, MICHAEL
Publication type:
Article
Neural Stem Cells as a Novel Platform for Tumor-Specific Delivery of Therapeutic Antibodies.
Published in:
PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008314
By:
- Frank, Richard T.;
- Edmiston, Marissa;
- Kendall, Stephen E.;
- Najbauer, Joseph;
- Chia-Wei Cheung;
- Kassa, Thewodros;
- Metz, Marianne Z.;
- Kim, Seung U.;
- Glackin, Carlotta A.;
- Wu, Anna M.;
- Yazaki, Paul J.;
- Aboody, Karen S.
Publication type:
Article
Multimodality PET and Near-Infrared Fluorescence Intraoperative Imaging of CEA-Positive Colorectal Cancer.
Published in:
Molecular Imaging & Biology, 2023, v. 25, n. 4, p. 727, doi. 10.1007/s11307-023-01831-8
By:
- Lwin, Thinzar M.;
- Minnix, Megan;
- Li, Lin;
- Sherman, Anakim;
- Hong, Teresa;
- Wong, Jeffery Y. C.;
- Olafsen, Tove;
- Poku, Erasmus;
- Bouvet, Michael;
- Fong, Yuman;
- Shively, John E.;
- Yazaki, Paul J.
Publication type:
Article
The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review.
Published in:
Biomolecules (2218-273X), 2021, v. 11, n. 12, p. 1819, doi. 10.3390/biom11121819
By:
- Turner, Michael A.;
- Lwin, Thinzar M.;
- Amirfakhri, Siamak;
- Nishino, Hiroto;
- Hoffman, Robert M.;
- Yazaki, Paul J.;
- Bouvet, Michael
Publication type:
Article
Accurate Co-Localization of Luciferase Expression and Fluorescent Anti-CEA Antibody Targeting of Liver Metastases in an Orthotopic Mouse Model of Colon Cancer.
Published in:
Cancers, 2024, v. 16, n. 19, p. 3341, doi. 10.3390/cancers16193341
By:
- Lee, Kyung-Ha;
- Cox, Kristin E.;
- Amirfakhri, Siamak;
- Jaiswal, Sunidhi;
- Liu, Shanglei;
- Hosseini, Mojgan;
- Lwin, Thinzar M.;
- Yazaki, Paul J.;
- Hoffman, Robert M.;
- Bouvet, Michael
Publication type:
Article
Enhanced Therapeutic Effects of 177 Lu-DOTA-M5A in Combination with Heat Shock Protein 90 Inhibitor Onalespib in Colorectal Cancer Xenografts.
Published in:
Cancers, 2023, v. 15, n. 17, p. 4239, doi. 10.3390/cancers15174239
By:
- Mohajershojai, Tabassom;
- Spangler, Douglas;
- Chopra, Saloni;
- Frejd, Fredrik Y.;
- Yazaki, Paul J.;
- Nestor, Marika
Publication type:
Article
ASO Visual Abstract: Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody.
Published in:
2024
By:
- Cox, Kristin E.;
- Turner, Michael A.;
- Lwin, Thinzar M.;
- Amirfakhri, Siamak;
- Kelly, Kaitlyn J.;
- Hosseini, Mojgan;
- Ghosh, Pradipta;
- Obonyo, Marygorret;
- Hoffman, Robert M.;
- Yazaki, Paul J.;
- Bouvet, Michael
Publication type:
Abstract
Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody.
Published in:
Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2024, v. 31, n. 9, p. 6291, doi. 10.1245/s10434-024-15570-9
By:
- Cox, Kristin E.;
- Turner, Michael A.;
- Lwin, Thinzar M.;
- Amirfakhri, Siamak;
- Kelly, Kaitlyn J.;
- Hosseini, Mojgan;
- Ghosh, Pradipta;
- Obonyo, Marygorret;
- Hoffman, Robert M.;
- Yazaki, Paul J.;
- Bouvet, Michael
Publication type:
Article
Comparison of IL‐2‐antibody to IL‐2‐Fc with or without stereotactic radiation therapy in CEA immunocompetent mice with CEA positive tumors.
Published in:
Cancer Medicine, 2024, v. 13, n. 3, p. 1, doi. 10.1002/cam4.6909
By:
- Williams, Lindsay;
- Li, Lin;
- Yazaki, Paul J.;
- Wong, Patty;
- Hong, Teresa;
- Poku, Erasmus K.;
- Hui, Susanta;
- Ghimire, Hemendra;
- Shively, John E.;
- Kujawski, Maciej
Publication type:
Article
Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors.
Published in:
EJNMMI Research, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13550-020-0600-z
By:
- Bäck, Tom A.;
- Jennbacken, Karin;
- Hagberg Thulin, Malin;
- Lindegren, Sture;
- Jensen, Holger;
- Olafsen, Tove;
- Yazaki, Paul J.;
- Palm, Stig;
- Albertsson, Per;
- Damber, Jan-Erik;
- Wu, Anna M.;
- Welén, Karin
Publication type:
Article
Pretargeting with Cucurbituril--Adamantane Host--Guest Pair in Xenograft Models.
Published in:
Journal of Nuclear Medicine, 2023, v. 64, n. 8, p. 1203, doi. 10.2967/jnumed.122.265008
By:
- Jallinoja, Vilma I. J.;
- Abbriano, Courtney H.;
- Bhatt, Kavita;
- Kaur, Amritjyot;
- Schlyer, David J.;
- Yazaki, Paul J.;
- Carney, Brandon D.;
- Houghton, Jacob L.
Publication type:
Article
Improved Tumor Responses with Sequential Targeted α-Particles Followed by Interleukin 2 Immunocytokine Therapies in Treatment of CEA-Positive Breast and Colon Tumors in CEA Transgenic Mice.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 12, p. 1859, doi. 10.2967/jnumed.122.264126
By:
- Minnix, Megan;
- Kujawski, Maciej;
- Poku, Erasmus;
- Yazaki, Paul J.;
- Wong, Jeffrey Y.;
- Shively, John E.
Publication type:
Article
Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 10, p. 1, doi. 10.2967/jnumed.122.264126
By:
- Minnix, Megan;
- Kujawski, Maciej;
- Poku, Erasmus;
- Yazaki, Paul J.;
- Wong, Jeffrey Y.;
- Shively, John E.
Publication type:
Article
Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 9, p. 1, doi. 10.2967/jnumed.122.264126
By:
- Minnix, Megan;
- Kujawski, Maciej;
- Poku, Erasmus;
- Yazaki, Paul J.;
- Wong, Jeffrey Y.;
- Shively, John E.
Publication type:
Article
Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 7, p. 1, doi. 10.2967/jnumed.122.264126
By:
- Minnix, Megan;
- Maciej Kujawski;
- Poku, Erasmus;
- Yazaki, Paul J.;
- Wong, Jeffrey Y.;
- Shively, John E.
Publication type:
Article
TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium- 225 labeled DOTAylated-huCC49 antibody.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.243394
By:
- Minnix, Megan;
- Lin Li;
- Yazaki, Paul J.;
- Miller, Aaron D.;
- Chea, Junie;
- Poku, Erasmus;
- An Liu;
- Wong, Jeffrey Y. C.;
- Rockne, Russell C.;
- Colcher, David;
- Shively, John E.
Publication type:
Article
TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium- 225 labeled DOTAylated-huCC49 antibody.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.243394
By:
- Minnix, Megan;
- Lin Li;
- Yazaki, Paul J.;
- Miller, Aaron D.;
- Junie Chea;
- Poku, Erasmus;
- An Liu;
- Wong, Jeffrey Y. C.;
- Rockne, Russell C.;
- Colcher, David;
- Shively, John E.
Publication type:
Article
TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium225 labeled DOTAylated-huCC49 antibody.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.243394
By:
- Minnix, Megan;
- Lin Li;
- Yazaki, Paul J.;
- Miller, Aaron D.;
- Junie Chea;
- Poku, Erasmus;
- An Liu;
- Wong, Jeffrey Y. C.;
- Rockne, Russell C.;
- Colcher, David;
- Shively, John E.
Publication type:
Article
TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium-225 labeled DOT Aylated-hu CC49 antibody.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.243394
By:
- Minnix, Megan;
- Lin Li;
- Yazaki, Paul J.;
- Miller, Aaron D.;
- Chea, Junie;
- Poku, Erasmus;
- Liu, An;
- Wong, Jeffrey Y. C.;
- Rockne, Russell C.;
- Colcher, David;
- Shively, John E.
Publication type:
Article
TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium-225 labeled DOTAylated-huCC49 antibody.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 7, p. 1, doi. 10.2967/jnumed.120.243394
By:
- Megan Minnix;
- Lin Li;
- Yazaki, Paul J.;
- Miller, Aaron D.;
- Junie Chea;
- Poku, Erasmus;
- An Liu;
- Wong, Jeffrey Y. C.;
- Rockne, Russell C.;
- Colcher, David;
- Shively, John E.
Publication type:
Article
Quantitative ImmunoPET of Prostate Cancer Xenografts with 89Zr- and 124I-Labeled Anti-PSCA A11 Minibody.
Published in:
Journal of Nuclear Medicine, 2014, v. 55, n. 3, p. 452, doi. 10.2967/jnumed.113.120873
By:
- Knowles, Scott M.;
- Zettlitz, Kirstin A.;
- Tavaré, Richard;
- Rochefort, Matthew M.;
- Salazar, Felix B.;
- Stout, David B.;
- Yazaki, Paul J.;
- Reiter, Robert E.;
- Wu, Anna M.
Publication type:
Article
Monodispersed DOTA-PEG-Conjugated Anti-TAG-72 Diabody Has Low Kidney Uptake and High Tumor-to-Blood Ratios Resulting in Improved 64Cu PET.
Published in:
Journal of Nuclear Medicine, 2010, v. 51, n. 7, p. 1139, doi. 10.2967/jnumed.109.074153
By:
- Lin Li;
- Turatti, Fabio;
- Crow, Desiree;
- Bading, James R.;
- Anderson, Anne-Line;
- Poku, Erasmus;
- Yazaki, Paul J.;
- Williams, Lawrence E.;
- Tamvakis, Debra;
- Sanders, Paul;
- Leong, David;
- Raubitschek, Andrew;
- Hudsony, Peter J.;
- Colchery, David;
- Shively, John E.
Publication type:
Article
Truncation of blood curves to enhance imaging and therapy with monoclonal antibodies.
Published in:
Medical Physics, 2000, v. 27, n. 5, p. 988, doi. 10.1118/1.598963
By:
- Williams, Lawrence E.;
- Liu, An;
- Wu, Anna M.;
- Yazaki, Paul J.;
- Yamauchi, Dave M.;
- Lopatin, George;
- Raubitschek, Andrew A.;
- Wong, Jeffrey Y. C.
Publication type:
Article
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Published in:
Nature, 2015, v. 517, n. 7534, p. 386, doi. 10.1038/nature13848
By:
- Huang, Yu-Hwa;
- Zhu, Chen;
- Kondo, Yasuyuki;
- Anderson, Ana C.;
- Gandhi, Amit;
- Russell, Andrew;
- Dougan, Stephanie K.;
- Petersen, Britt-Sabina;
- Melum, Espen;
- Pertel, Thomas;
- Clayton, Kiera L.;
- Raab, Monika;
- Chen, Qiang;
- Beauchemin, Nicole;
- Yazaki, Paul J.;
- Pyzik, Michal;
- Ostrowski, Mario A.;
- Glickman, Jonathan N.;
- Rudd, Christopher E.;
- Ploegh, Hidde L.
Publication type:
Article
In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.849338
By:
- Mohajershojai, Tabassom;
- Jha, Preeti;
- Boström, Anna;
- Frejd, Fredrik Y.;
- Yazaki, Paul J.;
- Nestor, Marika
Publication type:
Article
Generation of IL‐2‐Fc‐antibody conjugates by click chemistry.
Published in:
Biotechnology Journal, 2023, v. 18, n. 9, p. 1, doi. 10.1002/biot.202300115
By:
- Williams, Lindsay;
- Li, Lin;
- Yazaki, Paul J.;
- Wong, Patty;
- Miller, Aaron;
- Hong, Teresa;
- Poku, Erasmus K.;
- Bhattacharya, Supriyo;
- Shively, John E.;
- Kujawski, Maciej
Publication type:
Article
T‐cell surface generation of dual bivalent, bispecific T‐cell engaging, RNA duplex cross‐linked antibodies (dbBiTERs) for re‐directed tumor cell lysis.
Published in:
Biotechnology Journal, 2022, v. 17, n. 2, p. 1, doi. 10.1002/biot.202100389
By:
- Kujawski, Maciej;
- Li, Lin;
- Li, Harry;
- Yazaki, Paul J.;
- Swiderski, Piotr;
- Shively, John E.
Publication type:
Article
A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance.
Published in:
PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 3, p. 187, doi. 10.1093/protein/gzs096
By:
- Yazaki, Paul J.;
- Lee, Brian;
- Channappa, Divya;
- Cheung, Chia-Wei;
- Crow, Desiree;
- Chea, Junie;
- Poku, Erasmus;
- Li, Lin;
- Andersen, Jan Terje;
- Sandlie, Inger;
- Orcutt, Kelly Davis;
- Wittrup, K.Dane;
- Shively, John E.;
- Raubitschek, Andrew;
- Colcher, David
Publication type:
Article
Humanization of the anti-CEA T84.66 antibody based on crystal structure data.
Published in:
PEDS: Protein Engineering, Design & Selection, 2004, v. 17, n. 5, p. 481, doi. 10.1093/protein/gzh056
By:
- Paul J. Yazaki;
- John E. Shively;
- David Ikle;
- Lawrence E. Williams;
- Jeffrey Y.C. Wong;
- David Colcher;
- Anna M. Wu;
- Andrew A. Raubitschek
Publication type:
Article
Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting.
Published in:
PEDS: Protein Engineering, Design & Selection, 2004, v. 17, n. 4, p. 315, doi. 10.1093/protein/gzh040
By:
- Olafsen, Tove;
- Tan, Giselle J.;
- Cheung, Chia-wei;
- Yazaki, Paul J.;
- Park, Jinha M.;
- Shively, John E.;
- Williams, Lawrence E.;
- Raubitschek, Andrew A.;
- Press, Michael F.;
- Wu, Anna M.
Publication type:
Article
Covalent disulfide‐linked anti‐CEA diabody allows site‐specific conjugation and radiolabeling for tumor targeting applications.
Published in:
PEDS: Protein Engineering, Design & Selection, 2004, v. 17, n. 1, p. 21, doi. 10.1093/protein/gzh009
By:
- Tove Olafsen;
- Chia‐wei Cheung;
- Paul J. Yazaki;
- Lin Li;
- Gobalakrishnan Sundaresan;
- Sanjiv S. Gambhir;
- Mark A. Sherman;
- Lawrence E. Williams;
- John E. Shively;
- Andrew A. Raubitschek;
- Anna M. Wu
Publication type:
Article
124I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice.
Published in:
Journal of Nuclear Medicine, 2003, v. 44, n. 12, p. 1962
By:
- Sundaresan, Gobalakrishnan;
- Yazaki, Paul J.;
- Shively, John E.;
- Finn, Ronald D.;
- Larson, Steven M.;
- Raubitschek, Andrew A.;
- Williams, Lawrence E.;
- Chatziioannou, Arion F.;
- Gambhir, Sanjiv S.;
- Wu, Anna M.
Publication type:
Article

Found: 33

Improved antibody-guided surgery with a near-infrared dye on a pegylated linker for CEA-positive tumors.

Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models.

Neural Stem Cells as a Novel Platform for Tumor-Specific Delivery of Therapeutic Antibodies.

Multimodality PET and Near-Infrared Fluorescence Intraoperative Imaging of CEA-Positive Colorectal Cancer.

The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review.

Accurate Co-Localization of Luciferase Expression and Fluorescent Anti-CEA Antibody Targeting of Liver Metastases in an Orthotopic Mouse Model of Colon Cancer.

Enhanced Therapeutic Effects of 177 Lu-DOTA-M5A in Combination with Heat Shock Protein 90 Inhibitor Onalespib in Colorectal Cancer Xenografts.

ASO Visual Abstract: Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody.

Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody.

Comparison of IL‐2‐antibody to IL‐2‐Fc with or without stereotactic radiation therapy in CEA immunocompetent mice with CEA positive tumors.

Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors.

Pretargeting with Cucurbituril--Adamantane Host--Guest Pair in Xenograft Models.

Improved Tumor Responses with Sequential Targeted α-Particles Followed by Interleukin 2 Immunocytokine Therapies in Treatment of CEA-Positive Breast and Colon Tumors in CEA Transgenic Mice.

Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.

Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.

Improved tumor responses with sequential targeted alpha followed by IL2 immunocytokine therapies in treatment of CEA positive breast and colon tumors in CEA transgenic mice.

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium- 225 labeled DOTAylated-huCC49 antibody.

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium- 225 labeled DOTAylated-huCC49 antibody.

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium225 labeled DOTAylated-huCC49 antibody.

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium-225 labeled DOT Aylated-hu CC49 antibody.

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium-225 labeled DOTAylated-huCC49 antibody.

Quantitative ImmunoPET of Prostate Cancer Xenografts with <sup>89</sup>Zr- and <sup>124</sup>I-Labeled Anti-PSCA A11 Minibody.

Monodispersed DOTA-PEG-Conjugated Anti-TAG-72 Diabody Has Low Kidney Uptake and High Tumor-to-Blood Ratios Resulting in Improved <sup>64</sup>Cu PET.

Truncation of blood curves to enhance imaging and therapy with monoclonal antibodies.

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

In Vitro Characterization of <sup>177</sup>Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.

Generation of IL‐2‐Fc‐antibody conjugates by click chemistry.

T‐cell surface generation of dual bivalent, bispecific T‐cell engaging, RNA duplex cross‐linked antibodies (dbBiTERs) for re‐directed tumor cell lysis.

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance.

Humanization of the anti-CEA T84.66 antibody based on crystal structure data.

Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting.

Covalent disulfide‐linked anti‐CEA diabody allows site‐specific conjugation and radiolabeling for tumor targeting applications.

<sup>124</sup>I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice.