We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Development and psychometric evaluation of a chronic liver disease-specific quality of life questionnaire.
- Authors
Eun-Hyun Lee; Jae Youn Cheong; Sung Won Cho; Ki-Baik Hahm; Hak Yang Kim; Jong-Jae Park; Dong Ho Lee; Seong Kook Kim; Seok Reyol Choi; Soo Teik Lee; Seong Mi Moon
- Abstract
Background and Aims: There has been no reliable and valid instrument to measure health-related quality of life for Asian patients with chronic liver disease. The aim of the present study was to develop and evaluate a chronic liver disease-specific quality of life (CLD-QOL) questionnaire for Korean patients with chronic liver disease. Methods: Content-validated items were evaluated psychometrically in 271 patients with chronic liver disease recruited from seven university hospitals in Korea. The participants were asked to complete a preliminary questionnaire comprising the content-validated items and the Short Form-36 Health Survey. The Child–Pugh classification was used to classify the severity of liver cirrhosis. Results: Factor analysis extracted a five-factor solution from 27 preliminary items, which were generated by an expert panel and a pilot study, but factor and a multidimensional scaling analysis revealed that four items were not loaded significantly on any factor, suggesting that the four items might be heterogeneous. After deletion of these four items, a multiscaling analysis strongly supported item convergence and discriminant validity. The CLD-QOL was associated significantly with the Child–Pugh classification and the type of patient status (inpatient/outpatient) and was moderately correlated with the subscales of the Short Form-36 Health Survey. The values of Cronbach's alpha for the subscales of the novel CLD-QOL questionnaire were all greater than 0.70. Conclusions: The novel CLD-QOL questionnaire we developed is an easily applicable tool that exhibits excellent psychometric properties for Korean patients with chronic liver disease. It is recommended for the CLD-QOL to apply for Asian patients with chronic liver disease.
- Subjects
LIVER diseases; QUALITY of life; PSYCHOMETRICS; HEALTH surveys; GASTROENTEROLOGY; KOREANS; ASIANS
- Publication
Journal of Gastroenterology & Hepatology, 2008, Vol 23, Issue 2, p231
- ISSN
0815-9319
- Publication type
Article
- DOI
10.1111/j.1440-1746.2007.05034.x