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- Title
Pharmacokinetics of SDZ RAD and cyclosporin including their metabolites in seven kidney graft patients after the first dose of SDZ RAD.
- Authors
Kirchner, Gabriele I.; Winkler, Michael; Mueller, Lueke; Vidal, Christian; Jacobsen, Wolfgang; Franzke, Anke; Wagner, Siegfried; Blick, Stefan; Manns, Michael P.; Sewing, Karl-Friedrich
- Abstract
Investigates the pharmacokinetics and metabolism of the macrolide immunosuppressant in renal transplant patients. Metabolite pattern of cyclosporin; Influence of the immunosuppressants on the pharmacokinetics of cyclosporin; Role of cytochrome in metabolizing tacrolimus and rapamycin.
- Subjects
PHARMACOKINETICS; IMMUNOSUPPRESSIVE agents; KIDNEY transplantation; CYTOCHROMES
- Publication
British Journal of Clinical Pharmacology, 2000, Vol 50, Issue 5, p449
- ISSN
0306-5251
- Publication type
Article
- DOI
10.1046/j.1365-2125.2000.00293.x