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- Title
Efficacy of Cardiac Strain Imaging in predicting ischemic heart disease in patients presenting with non specific chest pain and normal LV ejection fraction.
- Authors
Sharma, Atin; Singh, Akhilesh; Saini, Neeraj
- Abstract
Objective: The objectives of this study were to evaluate the performance of LVGLS in the detection of severe coronary disease in patients with chest pain suggestive of NSTE-ACS as well as the associations between LVGLS reduction and elevation of ultrasensitive Troponin T (UsTnT), changes in electrocardiography suggestive of ischemia, and the number of severely occluded vessels. Methodology: Inpatients with suspected coronary artery disease and chest discomfort were evaluated in this prospective, observational investigation. All patients had electrocardiography (ECG), usTnT measurement, Doppler echocardiography, LVGLS measurement, and coronary angiography within 48 hours of being admitted to the hospital (CA). Results: There were a total of 75 patients, with a mean age of 58 17 years. Of these, 63 patients (or 84% of the total patient population) were men. Significant coronary blockages (lesions >70%) were found to be easier to spot when the Youden index LVGLS score was -16.5. Their values were 96%, 88%, 92%, and 92% for sensitivity, specificity, positive, and negative predictive values, respectively. The number of coronary arteries damaged was directly linked (P 0.001) with the extent of LVGLS reduction. Patients with lower LVGLS were more likely to have elevated UsTnT levels (83% vs. 17%, P 0.0001) than those with normal LVGLS. Abnormal strain was not associated with electrocardiographic anomalies that would have indicated ischemia. Conclusion: In individuals with suspected NSTE-ACS, LVGLS testing is successful in identifying the presence of severe coronary disease. The quantity of coronary arteries damaged directly correlates with the magnitude of LVGLS reduction. Increases in UsTnT are associated with aberrant strain but not with changes brought on by electrocardiographic ischemia.
- Subjects
CHEST pain; MYOCARDIAL ischemia; CARDIAC patients; CORONARY disease; CARDIAC imaging; VENTRICULAR ejection fraction
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2023, Vol 14, Issue 6, p2584
- ISSN
0975-3583
- Publication type
Article