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- Title
The Relationship Between Serum 25-Hydroxyvitamin D and Clinical and Subclinical Features in Hypertensive Patients with Coronary Artery Disease.
- Authors
Minh, Huynh Van; Tuan, Tran Ngoc; Duy, Le Van; Binh, Ho Anh; Giang, Pham Hong; Thang, Doan Chi; Lam, Nguyen Viet
- Abstract
Background: Vitamin D deficiency increases the risk of many acute and chronic diseases such as type 1 diabetes, cardiovascular disease, several cancers, cognitive impairment, depression, pregnancy complications, autoimmune disease. This study aims to investigate the relationship between serum 25- hydroxy vitamin D and clinical and subclinical features in hypertensive patients with coronary artery disease Methods: A cross-sectional descriptive was carried out in hypertensive patients with coronary artery stenosis by coronary. Results: The serum 25(OH)D level was a statistically significant different between the patients with different hypertension grades. The level of 25(OH)D was highest in patients with grade I hypertension and lowest in patients with grade III hypertension. The cut-off point of 25(OH)D in predicting grade IIIII hypertension was < 23.88 ng/ml; AUC = 95.9%, (p < 0.05). Blood cholesterol was negative correlation with serum 25(OH)D level and the correlation coefficient r = -0.205 with p>0.05. White blood cells was positive correlation with the serum 25(OH)D level and the correlation coefficient r = 0.366 with p > 0.05. Gensini score was negative correlation with serum 25(OH)D level and the correlation coefficient r = - 0.150 with p > 0.05. Conclusion: The serum 25(OH)D level was a statistically significant difference between the patients with different hypertension grades and there was no correlation with the Gensini score.
- Subjects
CORONARY artery disease; HYPERTENSION; CORONARY artery stenosis; CARDIOVASCULAR diseases; TYPE 1 diabetes
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2021, Vol 12, Issue 3, p1923
- ISSN
0975-3583
- Publication type
Article