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- Title
Effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV40-immortalized rabbit proximal tubule epithelial cells.
- Authors
Becker, Bryan N.; Kondo, Satoshi; Hui-Feng Cheng; Harris, Raymond C.
- Abstract
The article presents information on the effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV4O-immortalized rabbit proximal tubule epithelial cells. Ambient glucose concentrations can affect many aspects of renal cellular function including sodium-glucose co-transport, protein glycosylation, cellular hypertrophy, synthesis of transforming growth factor-Β and matrix accumalation. Ambient glucose levels also affect type 1 angiotensin II receptor expression in cells cultured from different sites in the kidney.
- Subjects
GLUCOSE; PYRUVATES; INSULIN; EPITHELIAL cells; KIDNEYS; ANGIOTENSINS
- Publication
Kidney International, 1997, Vol 52, Issue 1, p87
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.1997.307