We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Clinical effects of local application of collagen film-immobilized tetracycline.
- Authors
Minabe, Masato; Takeuchi, Kayo; Tomomatsu, Eiko; Hori, Toshio; Umemoto, Toshio
- Abstract
Tetracycline-containing cross-linked collagen film (TC film), or tetracycline-free placebo film, were locally applied 4 times, at 1-week intervals, to 33 teeth with periodontal pockets larger than 4 mm, in 11 patients with periodontal disease. The clinical and microbiological effects are summarized, as follows. In the group treated with the TC film, (1) the clinical indices were significantly decreased at the 4th and 7th weeks in comparison with those at the beginning of treatment. In particular, this group showed a significant decrease in the incidence of bleeding as compared with the placebo group at the 4th week. (2) Total counts of bacteria in the periodontal pockets showed an obvious tendency to decrease with time. The proportion of black-pigmented bacteroides was significantly decreased at the 4th and 7th weeks when compared with the pretreatment value. The extent of decrease in the proportion of spirochetes at both the 4th and 7th weeks was significant compared with the placebo group and the pretreatment value.
- Subjects
EXTRACELLULAR matrix proteins; COLLAGEN; DENTISTRY; HEMORRHAGE; PROKARYOTES; BACTEROIDES
- Publication
Journal of Clinical Periodontology, 1989, Vol 16, Issue 5, p291
- ISSN
0303-6979
- Publication type
Article
- DOI
10.1111/j.1600-051X.1989.tb01657.x