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Intranasal NAP (davunetide) decreases tau hyperphosphorylation and moderately improves behavioral deficits in mice overexpressing α-synuclein.
Published in:
Pharmacology Research & Perspectives, 2014, v. 2, n. 5, p. n/a, doi. 10.1002/prp2.65
By:
- Magen, Iddo;
- Ostritsky, Regina;
- Richter, Franziska;
- Zhu, Chunni;
- Fleming, Sheila M.;
- Lemesre, Vincent;
- Stewart, Alistair J.;
- Morimoto, Bruce H.;
- Gozes, Illana;
- Chesselet, Marie ‐ Françoise
Publication type:
Article
Farey Trees Explain Sequential Effects in Choice Response Time.
Published in:
Frontiers in Physiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphys.2021.611145
By:
- Annand, Colin T.;
- Fleming, Sheila M.;
- Holden, John G.
Publication type:
Article
Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein.
Published in:
Journal of Neuroscience, 2004, v. 24, n. 42, p. 9434, doi. 10.1523/JNEUROSCI.3080-04.2004
By:
- Fleming, Sheila M.;
- Salcedo, Jonathan;
- Fernagut, Pierre-Olivier;
- Rockenstein, Edward;
- Masliah, Eliezer;
- Levine, Michael S.;
- Chesselet, Marie-Françoise
Publication type:
Article
ATP13A2 (PARK9) and basal ganglia function.
Published in:
Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2023.1252400
By:
- Croucher, Kristina M.;
- Fleming, Sheila M.
Publication type:
Article
Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081426
By:
- Gombash, Sara E.;
- Manfredsson, Fredric P.;
- Kemp, Christopher J.;
- Kuhn, Nathan C.;
- Fleming, Sheila M.;
- Egan, Ann E.;
- Grant, Laura M.;
- Ciucci, Michelle R.;
- MacKeigan, Jeffrey P.;
- Sortwell, Caryl E.
Publication type:
Article
Cognitive dysfunction and increased phosphorylated tau are associated with reduced O‐GlcNAc signaling in an aging mouse model of metabolic syndrome.
Published in:
Journal of Neuroscience Research, 2023, v. 101, n. 8, p. 1324, doi. 10.1002/jnr.25196
By:
- Gupta, Shreya;
- Jinka, Sanjay K. A.;
- Khanal, Saugat;
- Bhavnani, Neha;
- Almashhori, Fayez;
- Lallo, Jason;
- Mathias, Amy;
- Al‐Rhayyel, Yasmine;
- Herman, Danielle;
- Holden, John G.;
- Fleming, Sheila M.;
- Raman, Priya
Publication type:
Article
Bacterial Artificial Chromosome Transgenic Mice Expressing a Truncated Mutant Parkin Exhibit Age-Dependent Hypokinetic Motor Deficits, Dopaminergic Neuron Degeneration, and Accumulation of Proteinase K-Resistant α-Synuclein.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 7, p. 1962, doi. 10.1523/JNEUROSCI.5351-08.2009
By:
- Xiao-Hong Lu;
- Fleming, Sheila M.;
- Meurers, Bernhard;
- Ackerson, Larry C.;
- Mortazavi, Farzad;
- Lo, Victor;
- Hernandez, Daniela;
- Sulzer, David;
- Jackson, George R.;
- Maidment, Nigel T.;
- Chesselet, Marie-Francoise;
- Yang, X. William
Publication type:
Article
3,4-Dihydroxyphenylalanine Reverses the Motor Deficits in Pitx3-Deficient Aphakia Mice: Behavioral Characterization of a Novel Genetic Model of Parkinson's Disease.
Published in:
Journal of Neuroscience, 2005, v. 25, n. 8, p. 2132, doi. 10.1523/JNEUROSCI.3718-04.2005
By:
- Dong-Youn Hwang;
- Fleming, Sheila M.;
- Ardayfio, Paul;
- Moran-Gates, Taylor;
- Hansoo Kim;
- Tarazi, Frank I.;
- Chesselet, Marie-Francoise;
- Kwang-Soo Kim
Publication type:
Article
Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre‐symptomatic female but not male htau mice.
Published in:
Neuropathology & Applied Neurobiology, 2021, v. 47, n. 7, p. 967, doi. 10.1111/nan.12711
By:
- Bretland, Katie A.;
- Lin, Li;
- Bretland, Kimberly M.;
- Smith, Matthew A.;
- Fleming, Sheila M.;
- Dengler‐Crish, Christine M.
Publication type:
Article
Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
Published in:
FASEB Journal, 2020, v. 34, n. 1, p. 1679, doi. 10.1096/fj.201900567RR
By:
- Neal, Matthew L.;
- Fleming, Sheila M.;
- Budge, Kevin M.;
- Boyle, Alexa M.;
- Kim, Chunki;
- Alam, Gelareh;
- Beier, Eric E.;
- Wu, Long‐Jun;
- Richardson, Jason R.
Publication type:
Article
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Published in:
Human Molecular Genetics, 2013, v. 22, n. 10, p. 2067, doi. 10.1093/hmg/ddt057
By:
- Schultheis, Patrick J.;
- Fleming, Sheila M.;
- Clippinger, Amy K.;
- Lewis, Jada;
- Tsunemi, Taiji;
- Giasson, Benoit;
- Dickson, Dennis W.;
- Mazzulli, Joseph R.;
- Bardgett, Mark E.;
- Haik, Kristi L.;
- Ekhator, Osunde;
- Chava, Anil Kumar;
- Howard, John;
- Gannon, Matt;
- Hoffman, Elizabeth;
- Yinhuai Chen;
- Prasad, Vikram;
- Linn, Stephen C.;
- Tamargo, Rafael J.;
- Westbroek, Wendy
Publication type:
Article
HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.
Published in:
Nature Neuroscience, 2011, v. 14, n. 1, p. 85, doi. 10.1038/nn.2692
By:
- Chan, C. Savio;
- Glajch, Kelly E.;
- Gertler, Tracy S.;
- Guzman, Jaime N.;
- Mercer, Jeff N.;
- Lewis, Alan S.;
- Goldberg, Alan B.;
- Tkatch, Tatiana;
- Shigemoto, Ryuichi;
- Fleming, Sheila M.;
- Chetkovich, Dane M.;
- Osten, Pavel;
- Kita, Hitoshi;
- Surmeier, D. James
Publication type:
Article
Cognitive deficits in a mouse model of pre-manifest Parkinson's disease.
Published in:
European Journal of Neuroscience, 2012, v. 35, n. 6, p. 870, doi. 10.1111/j.1460-9568.2012.08012.x
By:
- Magen, Iddo;
- Fleming, Sheila M.;
- Zhu, Chunni;
- Garcia, Eddie C.;
- Cardiff, Katherine M.;
- Dinh, Diana;
- De La Rosa, Krystal;
- Sanchez, Maria;
- Torres, Eileen Ruth;
- Masliah, Eliezer;
- David Jentsch, J.;
- Chesselet, Marie‐Françoise
Publication type:
Article
Olfactory deficits in mice overexpressing human wildtype α-synuclein.
Published in:
European Journal of Neuroscience, 2008, v. 28, n. 2, p. 247, doi. 10.1111/j.1460-9568.2008.06346.x
By:
- Fleming, Sheila M.;
- Tetreault, Nicole A.;
- Mulligan, Caitlin K.;
- Hutson, Ché B.;
- Masliah, Eliezer;
- Chesselet, Marie‐Françoise
Publication type:
Article
Impaired baroreflex function in mice overexpressing alpha-synuclein.
Published in:
Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00103
By:
- Fleming, Sheila M.;
- Jordan, Maria C.;
- Mulligan, Caitlin K.;
- Masliah, Eliezer;
- Holden, John G.;
- Millard, Ronald W.;
- Chesselet, Marie-Françoise;
- Roos, Kenneth P.
Publication type:
Article
Cinnamon in a mouse model of PD: Khasnavis S, Pahan K. Cinnamon protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol 2014;9:569-581.
Published in:
2014
By:
- Fleming, Sheila M.;
- Espay, Alberto J.
Publication type:
Editorial
Ribosomal s15: A novel therapeutic target for Parkinson's disease.
Published in:
2014
By:
- Fleming, Sheila M.;
- Espay, Alberto J.
Publication type:
Editorial

Found: 17