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- Title
Corynebacterium diphtheriae Infection in Mahajanga, Madagascar: First Case Report.
- Authors
Rakotomalala, Rivo Solotiana; Andrianirina, Zo Zafitsara; Ratsima, Elisoa; Randrianandraina, Patrick; Randrianirina, Frédérique; Edosoa, Glenn Torrencelli; Rabenandrianina, Tahirimalala; Badell, Edgar; Toubiana, Julie; Andrianarimanana, Diavolana; Brisse, Sylvain; Rasamindrakotroka, Andry
- Abstract
Diphtheria is an infection that has been unreported for more than two decades in Mahajanga. A child, aged 4, presented with a pseudomembranous pharyngitis was associated with a dysphagia. He was from a rural municipality of Ambato Boeny at Mahajanga province and was admitted to the Pediatric Unit of the University Hospital Center. The child was not immunized against diphtheria. A throat swab was performed and cultured, from which Corynebacterium diphtheriae was identified. The strain, of biovar Mitis, was confirmed as diphtheria toxin (DT)-gene positive and produced DT (Elek test). Unfortunately, the child developed cardiac and neurological complications and died of respiratory and heart failure.
- Subjects
MADAGASCAR; DIPHTHERIA toxin; CORYNEBACTERIUM; DIPHTHERIA; INFECTION; RESPIRATORY insufficiency; GRAM-positive bacteria; PHARYNGITIS
- Publication
Journal of Tropical Pediatrics, 2021, Vol 67, Issue 1, p1
- ISSN
0142-6338
- Publication type
journal article
- DOI
10.1093/tropej/fmaa064