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- Title
Characterization of disordered proteins with ENSEMBLE.
- Authors
Krzeminski, Mickaël; Marsh, Joseph A.; Neale, Chris; Choy, Wing-Yiu; Forman-Kay, Julie D.
- Abstract
Summary: ENSEMBLE is a computational approach for determining a set of conformations that represents the structural ensemble of a disordered protein based on input experimental data. The disordered protein can be an unfolded or intrinsically disordered state. Here, we introduce the latest version of the program, which has been enhanced to facilitate its general release and includes an intuitive user interface, as well as new approaches to treat data and analyse results.Availability and implementation: ENSEMBLE is a program implemented in C and embedded in a Perl wrapper. It is supported on main Linux distributions. Source codes and installation files, including a detailed example, can be freely downloaded at http://abragam.med.utoronto.ca/∼JFKlab.Contact: forman@sickkids.caSupplementary information: Supplementary Material are available at Bioinformatics online.
- Subjects
PROTEIN conformation; PROTEIN structure; BIOINFORMATICS; LINUX operating systems; COMPUTER software installation; DATA analysis
- Publication
Bioinformatics, 2013, Vol 29, Issue 3, p398
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/bts701