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- Title
Quality of life by proxy and mortality in institutionalized older adults with dementia.
- Authors
González‐Vélez, Abel E; Forjaz, María Joao; Giraldez‐García, Carolina; Martín‐García, Salomé; Martínez‐Martín, Pablo
- Abstract
Aim This study aimed at analyzing the effect of quality of life ( QoL) on mortality in older adults with dementia living in long-term care facilities. Methods A prospective observational cohort study was carried out on 412 residents aged older than 60 years, diagnosed with dementia according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. Besides assessment of QoL ( EQ-5D index by proxy) and perceived health status ( EQ-VAS), baseline measurements included severity of dementia ( Clinical Dementia Rating Scale [ CDR]), comorbidity (number of self-reported chronic conditions), disability evaluation ( Barthel Index), cognitive state ( Mini Examen Cognoscitivo, a validated and modified Spanish version of the Mini- Mental State Examination) and depression ( Cornell Depression Scale for Dementia). Sociodemographic and clinical variables were analyzed as potential effect modifiers and confounders in the relationship between QoL and mortality using a multivariate logistic regression analysis. Results After an 18-month follow up, 138 residents had died. Adjusting for CDR and Barthel Index, the odds of mortality were multiplied by 0.25 (95% CI 0.09-0.70) and 0.79 (95% CI 0.26-2.42) for every unit of change in the EQ-5D index in the residents with Cornell score <6 and ≥6, respectively. Conclusion The present study suggests that the effect of QoL on mortality in institutionalized adults with dementia should take into account the presence or absence of depression. In addition, residents with a greater disability and more advanced dementia should be a target for interventions in rehabilitation care. Geriatr Gerontol Int 2015; 15: 38-44.
- Subjects
CONFIDENCE intervals; DEMENTIA; MENTAL depression; HEALTH status indicators; LONGITUDINAL method; MORTALITY; NURSING care facilities; QUALITY of life; QUESTIONNAIRES; ACTIVITIES of daily living; SOCIOECONOMIC factors; VISUAL analog scale; SEVERITY of illness index
- Publication
Geriatrics & Gerontology International, 2015, Vol 15, Issue 1, p38
- ISSN
1444-1586
- Publication type
Article
- DOI
10.1111/ggi.12225