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Developmental pyrethroid exposure and age influence phenotypes in a Chd8 haploinsufficient autism mouse model.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09533-x
By:
- Jiménez, Jessica A.;
- Simon, Jeremy M.;
- Hu, Wenxin;
- Moy, Sheryl S.;
- Harper, Kathryn M.;
- Liu, Chih-Wei;
- Lu, Kun;
- Zylka, Mark J.
Publication type:
Article
Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses.
Published in:
European Journal of Immunology, 2016, v. 46, n. 8, p. 1912, doi. 10.1002/eji.201546237
By:
- Simon, Jeremy M.;
- Davis, James P.;
- Lee, Saangyoung E.;
- Schaner, Matthew R.;
- Gipson, Gregory R.;
- Weiser, Matthew;
- Sartor, R. Balfour;
- Herfarth, Hans H.;
- Rahbar, Reza;
- Sadiq, Timothy S.;
- Koruda, Mark J.;
- McGovern, Dermot P.;
- Lieb, Jason D.;
- Mohlke, Karen L.;
- Furey, Terrence S.;
- Sheikh, Shehzad Z.
Publication type:
Article
Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
Published in:
2022
By:
- Ocasio, Jennifer Karin;
- Babcock, Benjamin;
- Malawsky, Daniel;
- Weir, Seth J.;
- Loo, Lipin;
- Simon, Jeremy M.;
- Zylka, Mark J.;
- Hwang, Duhyeong;
- Dismuke, Taylor;
- Sokolsky, Marina;
- Rosen, Elias P.;
- Vibhakar, Rajeev;
- Zhang, Jiao;
- Saulnier, Olivier;
- Vladoiu, Maria;
- El-Hamamy, Ibrahim;
- Stein, Lincoln D.;
- Taylor, Michael D.;
- Smith, Kyle S.;
- Northcott, Paul A.
Publication type:
Correction Notice
A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.
Published in:
Journal of Pathology, 2020, v. 252, n. 2, p. 125, doi. 10.1002/path.5504
By:
- Bowman, Brittany M;
- Montgomery, Stephanie A;
- Schrank, Travis P;
- Simon, Jeremy M;
- Ptacek, Travis S;
- Tamir, Tigist Y;
- Mulvaney, Kathleen M;
- Weir, Seth J;
- Nguyen, Tuong T;
- Murphy, Ryan M;
- Makowski, Liza;
- Hayes, D Neil;
- Chen, Xiaoxin L;
- Randell, Scott H;
- Weissman, Bernard E;
- Major, Michael B
Publication type:
Article
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation.
Published in:
PLoS Genetics, 2020, v. 16, n. 1, p. 1, doi. 10.1371/journal.pgen.1008537
By:
- Keele, Gregory R.;
- Quach, Bryan C.;
- Israel, Jennifer W.;
- Chappell, Grace A.;
- Lewis, Lauren;
- Safi, Alexias;
- Simon, Jeremy M.;
- Cotney, Paul;
- Crawford, Gregory E.;
- Valdar, William;
- Rusyn, Ivan;
- Furey, Terrence S.
Publication type:
Article
BET Protein Inhibition Regulates Macrophage Chromatin Accessibility and Microbiota-Dependent Colitis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.856966
By:
- Hoffner O'Connor, Michelle;
- Berglind, Ana;
- Kennedy Ng, Meaghan M.;
- Keith, Benjamin P.;
- Lynch, Zachary J.;
- Schaner, Matthew R.;
- Steinbach, Erin C.;
- Herzog, Jeremy;
- Trad, Omar K.;
- Jeck, William R.;
- Arthur, Janelle C.;
- Simon, Jeremy M.;
- Sartor, R. Balfour;
- Furey, Terrence S.;
- Sheikh, Shehzad Z.
Publication type:
Article
A map of open chromatin in human pancreatic islets.
Published in:
Nature Genetics, 2010, v. 42, n. 3, p. 255, doi. 10.1038/ng.530
By:
- Gaulton, Kyle J.;
- Nammo, Takao;
- Pasquali, Lorenzo;
- Simon, Jeremy M.;
- Giresi, Paul G.;
- Fogarty, Marie P.;
- Panhuis, Tami M.;
- Mieczkowski, Piotr;
- Secchi, Antonio;
- Bosco, Domenico;
- Berney, Thierry;
- Montanya, Eduard;
- Mohlke, Karen L.;
- Lieb, Jason D.;
- Ferrer, Jorge
Publication type:
Article
Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.72290
By:
- Hyojin Kim;
- Gao, Eric B.;
- Draper, Adam;
- Berens, Noah C.;
- Vihma, Hanna;
- Xinyuan Zhang;
- Higashi-Howard, Alexandra;
- Simon, Jeremy M.;
- Kennedy, Andrew J.;
- Philpot, Benjamin D.
Publication type:
Article
ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.70412
By:
- Wentong Fang;
- Chengheng Liao;
- Shi, Rachel;
- Simon, Jeremy M.;
- Ptacek, Travis S.;
- Zurlo, Giada;
- Youqiong Ye;
- Leng Han;
- Cheng Fan;
- Lei Bao;
- Ortiz, Christopher Llynard;
- Hong-Rui Lin;
- Manocha, Ujjawal;
- Luo, Weibo;
- Yan Peng;
- Kim, William Y.;
- Lee-Wei Yang;
- Qing Zhang
Publication type:
Article
Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13168-4
By:
- Zurlo, Giada;
- Liu, Xijuan;
- Takada, Mamoru;
- Fan, Cheng;
- Simon, Jeremy M.;
- Ptacek, Travis S.;
- Rodriguez, Javier;
- von Kriegsheim, Alex;
- Liu, Juan;
- Locasale, Jason W.;
- Robinson, Adam;
- Zhang, Jing;
- Holler, Jessica M.;
- Kim, Baek;
- Zikánová, Marie;
- Bierau, Jörgen;
- Xie, Ling;
- Chen, Xian;
- Li, Mingjie;
- Perou, Charles M.
Publication type:
Article
Single-cell transcriptomic analysis of mouse neocortical development.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08079-9
By:
- Loo, Lipin;
- Simon, Jeremy M.;
- Xing, Lei;
- McCoy, Eric S.;
- Niehaus, Jesse K.;
- Guo, Jiami;
- Anton, E. S.;
- Zylka, Mark J.
Publication type:
Article
A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance.
Published in:
Journal of Neurodevelopmental Disorders, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s11689-020-09332-3
By:
- Lee, Hyeong-Min;
- Kuijer, M. Bram;
- Ruiz Blanes, Nerea;
- Clark, Ellen P.;
- Aita, Megumi;
- Galiano Arjona, Lorena;
- Kokot, Agnieszka;
- Sciaky, Noah;
- Simon, Jeremy M.;
- Bhatnagar, Sanchita;
- Philpot, Benjamin D.;
- Cerase, Andrea
Publication type:
Article
Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
Published in:
Environmental Health Perspectives, 2017, v. 125, n. 10, p. 1, doi. 10.1289/EHP1937
By:
- Chappell, Grace A.;
- Israel, Jennifer W.;
- Simon, Jeremy M.;
- Pott, Sebastian;
- Safi, Alexias;
- Eklund, Karl;
- Sexton, Kenneth G.;
- Bodnar, Wanda;
- Lieb, Jason D.;
- Crawford, Gregory E.;
- Rusyn, Ivan;
- Furey, Terrence S.
Publication type:
Article
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Published in:
Advanced Science, 2023, v. 10, n. 3, p. 1, doi. 10.1002/advs.202203718
By:
- Zhu, Zhichuan;
- Zhou, Xin;
- Du, Hongwei;
- Cloer, Erica W.;
- Zhang, Jiaming;
- Mei, Liu;
- Wang, Ying;
- Tan, Xianming;
- Hepperla, Austin J.;
- Simon, Jeremy M.;
- Cook, Jeanette Gowen;
- Major, Michael B.;
- Dotti, Gianpietro;
- Liu, Pengda
Publication type:
Article
Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.
Published in:
Neuro-Oncology, 2018, v. 20, n. 9, p. 1237, doi. 10.1093/neuonc/nox050
By:
- Vitucci, Mark;
- Irvin, David M;
- McNeill, Robert S;
- Schmid, Ralf S;
- Simon, Jeremy M;
- Dhruv, Harshil D;
- Siegel, Marni B;
- Werneke, Andrea M;
- Bash, Ryan E;
- Kim, Seungchan
Publication type:
Article
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
Published in:
Neuro-Oncology, 2017, v. 19, n. 11, p. 1469, doi. 10.1093/neuonc/nox044
By:
- McNeill, Robert S.;
- Canoutas, Demitra A.;
- Stuhlmiller, Timothy J.;
- Dhruv, Harshil D.;
- Irvin, David M.;
- Bash, Ryan E.;
- Angus, Steven P.;
- Herring, Laura E.;
- Simon, Jeremy M.;
- Skinner, Kasey R.;
- Limas, Juanita C.;
- Xin Chen;
- Schmid, Ralf S.;
- Siegel, Marni B.;
- Van Swearingen, Amanda E. D.;
- Hadler, Michael J.;
- Sulman, Erik P.;
- Sarkaria, Jann N.;
- Anders, Carey K.;
- Graves, Lee M.
Publication type:
Article
Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.
Published in:
Neuro-Oncology, 2017, v. 19, n. 9, p. 1237, doi. 10.1093/neuonc/nox050
By:
- Vitucci, Mark;
- Irvin, David M.;
- McNeill, Robert S.;
- Schmid, Ralf S.;
- Simon, Jeremy M.;
- Dhruv, Harshil D.;
- Siegel, Marni B.;
- Werneke, Andrea M.;
- Bash, Ryan E.;
- Seungchan Kim;
- Berens, Michael E.;
- Miller, C. Ryan
Publication type:
Article
Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.
Published in:
Neuro-Oncology, 2016, v. 18, n. 7, p. 962, doi. 10.1093/neuonc/nov321
By:
- Schmid, Ralf S.;
- Simon, Jeremy M.;
- Vitucci, Mark;
- McNeill, Robert S.;
- Bash, Ryan E.;
- Werneke, Andrea M.;
- Huey, Lauren;
- White, Kristen K.;
- Ewend, Matthew G.;
- Jing Wu;
- Miller, C. Ryan
Publication type:
Article
Regional and cellular organization of the autism-associated protein UBE3A/E6AP and its antisense transcript in the brain of the developing rhesus monkey.
Published in:
Frontiers in Neuroanatomy, 2024, p. 1, doi. 10.3389/fnana.2024.1410791
By:
- Ramirez, Chavely Gonzalez;
- Salvador, Sarah G.;
- Rekha Patel, Ridthi Kartik;
- Clark, Sarah;
- Miller, Noah W.;
- James, Lucas M.;
- Ringelberg, Nicholas W.;
- Simon, Jeremy M.;
- Bennett, Jeffrey;
- Amaral, David G.;
- Burette, Alain C.;
- Philpot, Benjamin D.
Publication type:
Article
Gastrulation‐stage alcohol exposure induces similar rates of craniofacial malformations in male and female C57BL/6J mice.
Published in:
Birth Defects Research, 2024, v. 116, n. 1, p. 1, doi. 10.1002/bdr2.2292
By:
- Boschen, Karen E.;
- Dragicevich, Constance J.;
- Fish, Eric W.;
- Hepperla, Austin J.;
- Simon, Jeremy M.;
- Parnell, Scott E.
Publication type:
Article
The pro‐apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation‐stage alcohol exposure.
Published in:
Birth Defects Research, 2022, v. 114, n. 19, p. 1229, doi. 10.1002/bdr2.2009
By:
- Fish, Eric W.;
- Mendoza‐Romero, Haley N.;
- Love, Charlotte A.;
- Dragicevich, Constance J.;
- Cannizzo, Michael D.;
- Boschen, Karen E.;
- Hepperla, Austin;
- Simon, Jeremy M.;
- Parnell, Scott E.
Publication type:
Article
Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations.
Published in:
Human Molecular Genetics, 2024, v. 33, n. 5, p. 448, doi. 10.1093/hmg/ddad199
By:
- Williams, Brittany N;
- Draper, Adam;
- Lang, Patrick F;
- Lewis, Tylor R;
- Smith, Audrey L;
- Mayerl, Steven J;
- Rougié, Marie;
- Simon, Jeremy M;
- Arshavsky, Vadim Y;
- Greenwald, Scott H;
- Gamm, David M;
- Pinilla, Isabel;
- Philpot, Benjamin D
Publication type:
Article
Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.
Published in:
Nature Communications, 2016, v. 7, n. 3, p. 11173, doi. 10.1038/ncomms11173
By:
- Pearson, Brandon L.;
- Simon, Jeremy M.;
- McCoy, Eric S.;
- Salazar, Gabriela;
- Fragola, Giulia;
- Zylka, Mark J.
Publication type:
Article
Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disorders.
Published in:
Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1106573
By:
- Baker, Brennan H.;
- Shaoyi Zhang;
- Simon, Jeremy M.;
- McLarnan, Sarah M.;
- Chung, Wendy K.;
- Pearson, Brandon L.
Publication type:
Article
Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.
Published in:
PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0156439
By:
- Mabb, Angela M.;
- Simon, Jeremy M.;
- King, Ian F.;
- Lee, Hyeong-Min;
- An, Lin-Kun;
- Philpot, Benjamin D.;
- Zylka, Mark J.
Publication type:
Article
Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
Published in:
Mammalian Genome, 2018, v. 29, n. 1/2, p. 153, doi. 10.1007/s00335-018-9739-6
By:
- Israel, Jennifer W.;
- Chappell, Grace A.;
- Simon, Jeremy M.;
- Pott, Sebastian;
- Safi, Alexias;
- Lewis, Lauren;
- Cotney, Paul;
- Boulos, Hala S.;
- Bodnar, Wanda;
- Lieb, Jason D.;
- Crawford, Gregory E.;
- Furey, Terrence S.;
- Rusyn, Ivan
Publication type:
Article
Enhanced Nociception in Angelman Syndrome Model Mice.
Published in:
Journal of Neuroscience, 2017, v. 37, n. 42, p. 10230, doi. 10.1523/JNEUROSCI.1018-17.2017
By:
- McCoy, Eric S.;
- Taylor-Blake, Bonnie;
- Aita, Megumi;
- Simon, Jeremy M.;
- Philpot, Benjamin D.;
- Zylka, Mark J.
Publication type:
Article
High-throughput screening and classification of chemicals and their effects on neuronal gene expression using RASL-seq.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39016-5
By:
- Simon, Jeremy M.;
- Paranjape, Smita R.;
- Wolter, Justin M.;
- Salazar, Gabriela;
- Zylka, Mark J.
Publication type:
Article
Early life exposure to vitamin D deficiency impairs molecular mechanisms that regulate liver cholesterol biosynthesis, energy metabolism, inflammation, and detoxification.
Published in:
Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1335855
By:
- Knuth, Megan M.;
- Jing Xue;
- Elnagheeb, Marwa;
- Gharaibeh, Raad Z.;
- Schoenrock, Sarah A.;
- McRitchie, Susan;
- Brouwer, Cory;
- Sumner, Susan J.;
- Tarantino, Lisa;
- Valdar, William;
- Rector, R. Scott;
- Simon, Jeremy M.;
- Ideraabdullah, Folami
Publication type:
Article
Correction to: Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.
Published in:
2021
By:
- Jiménez, Jessica A.;
- Ptacek, Travis S.;
- Tuttle, Alex H.;
- Schmid, Ralf S.;
- Moy, Sheryl S.;
- Simon, Jeremy M.;
- Zylka, Mark J.
Publication type:
Correction Notice
Chd8 haploinsufficiency impairs early brain development and protein homeostasis later in life.
Published in:
Molecular Autism, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13229-020-00369-8
By:
- Jiménez, Jessica A.;
- Ptacek, Travis S.;
- Tuttle, Alex H.;
- Schmid, Ralf S.;
- Moy, Sheryl S.;
- Simon, Jeremy M.;
- Zylka, Mark J.
Publication type:
Article
Inside Cover: A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a (ChemMedChem 3/2014).
Published in:
ChemMedChem, 2014, v. 9, n. 3, p. 414, doi. 10.1002/cmdc.201490006
By:
- Konze, Kyle D.;
- Pattenden, Samantha G.;
- Liu, Feng;
- Barsyte‐Lovejoy, Dalia;
- Li, Fengling;
- Simon, Jeremy M.;
- Davis, Ian J.;
- Vedadi, Masoud;
- Jin, Jian
Publication type:
Article
A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a.
Published in:
ChemMedChem, 2014, v. 9, n. 3, p. 549, doi. 10.1002/cmdc.201300450
By:
- Konze, Kyle D.;
- Pattenden, Samantha G.;
- Liu, Feng;
- Barsyte‐Lovejoy, Dalia;
- Li, Fengling;
- Simon, Jeremy M.;
- Davis, Ian J.;
- Vedadi, Masoud;
- Jin, Jian
Publication type:
Article
Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15794-9
By:
- Fragola, Giulia;
- Mabb, Angela M.;
- Taylor-Blake, Bonnie;
- Niehaus, Jesse K.;
- Chronister, William D.;
- Mao, Hanqian;
- Simon, Jeremy M.;
- Yuan, Hong;
- Li, Zibo;
- McConnell, Michael J.;
- Zylka, Mark J.
Publication type:
Article
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13657-6
By:
- Ocasio, Jennifer;
- Babcock, Benjamin;
- Malawsky, Daniel;
- Weir, Seth J.;
- Loo, Lipin;
- Simon, Jeremy M.;
- Zylka, Mark J.;
- Hwang, Duhyeong;
- Dismuke, Taylor;
- Sokolsky, Marina;
- Rosen, Elias P.;
- Vibhakar, Rajeev;
- Zhang, Jiao;
- Saulnier, Olivier;
- Vladoiu, Maria;
- El-Hamamy, Ibrahim;
- Stein, Lincoln D.;
- Taylor, Michael D.;
- Smith, Kyle S.;
- Northcott, Paul A.
Publication type:
Article

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