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- Title
Prognostic importance of ultrasound BI-RADS classification in breast cancer patients.
- Authors
Ju-Yeon Kim; Eun Jung Jung; Taejin Park; Sang-Ho Jeong; Chi-Young Jeong; Young-Tae Ju; Young-Joon Lee; Soon-Chan Hong; Woo-Song Ha; Sang-Kyung Choi
- Abstract
Objective: We investigated the prognostic importance of pre-operative Breast Imaging Reporting and Data System classification in ultrasound imaging. Methods: Histopathological differences and disease-free survival were analyzed in Breast Imaging Reporting and Data System classification subgroups. Univariate and multivariate analyses were used to identify the prognostic factors. Results: We identified 531 invasive breast cancer patients eligible for this study. Most patients classified as Breast Imaging Reporting and Data System 5 had large tumors and a higher rate of lymph node metastasis. However, hormonal receptor or HER-2 status did not differ according to Breast Imaging Reporting and Data System classification. During a median post-operative follow-up of 42.0 months, 43 patients were diagnosed with a disease-specific event. Disease-free survival was significantly lower in patients with Breast Imaging Reporting and Data System 5 than in patients with Breast Imaging Reporting and Data System 3-4. Subgroup analysis of patients with invasive breast cancer of Stage I showed that Breast Imaging Reporting and Data System 5 was an independent negative prognostic indicator of disease-free survival (hazard ratio 9.195; 95% confidence interval, 1.175-71.955; P=0.035). Conclusions: Breast Imaging Reporting and Data System classification might be considered as prognostic factors especially in Stage I breast cancer. Further confirmatory studies are needed.
- Publication
Japanese Journal of Clinical Oncology, 2015, Vol 45, Issue 5, p411
- ISSN
0368-2811
- Publication type
Article
- DOI
10.1093/jjco/hyv018