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- Title
Study the effects of smoking on selected oral biomarkers levels in chronic periodontitis cases in Al-Hilla city.
- Authors
Hessan, Hanan Selman; Hameed, Zainab Muhi; Abood, Doaa Adil
- Abstract
Alkaline phosphatase (ALP) is a hydrolase enzyme, a membrane-based glycoprotein produced by many cells within the area of the periodontium and gingival crevice. Granulocyte-macrophage colony-stimulating factor (GMCSF) is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Subjects and method: the study comprised 40 participate, 25 smoker chronic periodontitis, 15 normal subject as control, age ranged between (20-50) years old, this study carried out in periodontal department clinic/collage of dentistry / university of Babylon, Hilla city, Iraq, 5 ml of unstimulated whole saliva was collected from all subjects to measure Alkaline phosphatase (ALP) and Granulocyte-macrophage colony-stimulating factor (GM-CSF) by Enzyme-linked immunosorbent assay technique (ELISA). Results: the result show there are highly -significant differences in the levels of(ALP and GM-CSF) between smoker and control. Conclusion: Smoking in chronic periodontitis patients has positive effects on levels of (ALP and GM-CSF) in saliva.
- Subjects
IRAQ; PERIODONTITIS; BABYLON (Extinct city); GRANULOCYTE-macrophage colony-stimulating factor; LEUCOCYTES; ENZYME-linked immunosorbent assay; ALKALINE phosphatase; STEM cells
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 8, p742
- ISSN
0975-8453
- Publication type
Article