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- Title
Alternative Macroautophagic Pathways.
- Authors
Juenemann, Katrin; Reits, Eric A.
- Abstract
Macroautophagy is a bulk degradation process that mediates the clearance of long-lived proteins, aggregates, or even whole organelles. This process includes the formation of autophagosomes, double-membrane structures responsible for delivering cargo to lysosomes for degradation. Currently, other alternative autophagy pathways have been described, which are independent of macroautophagic key players like Atg5 and Beclin 1 or the lipidation of LC3. In this review, we highlight recent insights in indentifying and understanding the molecular mechanism responsible for alternative autophagic pathways
- Subjects
AUTOPHAGY; CELL membrane models; LYSOSOMES; PROTEOLYSIS; ISOPRENYLATION; MOLECULAR biology; MEDICAL literature reviews; ORGANELLES
- Publication
International Journal of Cell Biology, 2012, p1
- ISSN
1687-8876
- Publication type
Article
- DOI
10.1155/2012/189794