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- Title
Serotonergic Neurotransmission in the Living Human Brain: A Positron Emission Tomography Study Using [11C] DASB and [11C] WAY100635 in Young Healthy Men.
- Authors
TAKANO, HARUMASA; ITO, HIROSHI; TAKAHASHI, HIDEHIKO; ARAKAWA, RYOSUKE; OKUMURA, MASAKI; KODAKA, FUMITOSHI; OTSUKA, TATSUI; KATO, MOTOICHIRO; SUHARA, TETSUYA
- Abstract
The article presents a study on the central serotonergic (5-HT) system of the human brain to examine the serotonergic neurotransmission in the living human brain. In the study, 17 healthy males underwent magnetic resonance imaging (MRI) of the brain. The positron emission tomography (PET) was also used in the study. It claims that dysregulation of the 5-HT system could lead to various neuropsychiatric ailments like schizophrenia, as well as mood and anxiety disorders.
- Subjects
BRAIN research; SEROTONINERGIC mechanisms; NEURAL transmission; MAGNETIC resonance imaging of the brain; POSITRON emission tomography; NEUROBEHAVIORAL disorders
- Publication
Synapse, 2011, Vol 65, Issue 7, p624
- ISSN
0887-4476
- Publication type
Article
- DOI
10.1002/syn.20883