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- Title
Indices of disease activity in psoriatic arthritis.
- Authors
Daunt, A. O'N.; Cox, N. L.; Robertson, J. C.; Cawley, M. I. D.
- Abstract
Psoriatic arthritis (PA) may respond to disease-modifying antirheumatic therapy. The value of assessing disease activity with indices devised for rheumatoid arthritis (RA) was investigated in 72 patients with seronegative PA. Thirty patients had a peripheral polyarthritis including the distal interphalangeal joints (DIPJs) and 15 a symmetrical arthritis sparing DIPJs (RA-like). Significant correlations (Spearman rank test) were seen between the clinical variables (pain score, grip strength, Ritchie articular index and a summated index of disease activity) in these two groups. Ten patients with a markedly asymmetrical arthritis showed a poor correlation between clinical variables. Although the objective indices -- erythrocyte sedimentation rate (ESR) and C-reactive protein -- correlated together in the first two groups, the ESR correlated solely with clinical indices, and then only in RA-like patients. These results cast some doubt on the value of assessment methods based on RA when evaluating subgroups of PA other than RA-like disease.
- Subjects
PSORIATIC arthritis; ANTIRHEUMATIC agents; RHEUMATOID arthritis; PATIENTS; JOINTS (Anatomy)
- Publication
Journal of the Royal Society of Medicine, 1987, Vol 80, Issue 9, p556
- ISSN
0141-0768
- Publication type
Article
- DOI
10.1177/014107688708000907