We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Prolonged refractory status epilepticus with early and persistent restricted hippocampal signal MRI abnormality.
- Authors
Chevret, Laurent; Husson, Beatrice; Nguefack, Seraphin; Nehlig, Astrid; Bouilleret, Viviane
- Abstract
We report a series of four children with a prolonged refractory status epilepticus with an early persistent and restricted hippocampal signal MRI abnormality but otherwise no proven etiology. The mean duration of status epilepticus was 53 days (range, 20–91 days) with a mean length of stay in Pediatric Intensive Care Unit (PICU) of 2 months (range, 26–115 days). Neurological outcome showed epilepsy disease in all, and mild to severe disability. In long-term follow-up, the initial MRI signal abnormality developed into a cortical atrophy in all cases. The establishment of the diagnosis, etiology, and options for treatment are discussed.
- Subjects
EPILEPSY; HIPPOCAMPUS (Brain); MAGNETIC resonance imaging; CHILDREN; PLASMAPHERESIS
- Publication
Journal of Neurology, 2008, Vol 255, Issue 1, p112
- ISSN
0340-5354
- Publication type
Article
- DOI
10.1007/s00415-008-0713-1