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- Title
Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma.
- Authors
GU-SHUN LAI; JIAN-RI LI; SHIAN-SHIANG WANG; CHUAN-SHU CHEN; CHUN-KUANG YANG; SHENG-CHUN HUNG; CHEN-LI CHENG; YEN-CHUAN OU; KUN-YUAN CHIU
- Abstract
Background/Aim: To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. Patients and Methods: We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution. Results: At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.10- 3.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048). Conclusion: For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI.
- Subjects
PROGNOSTIC tests; RENAL cell carcinoma; PATHOLOGY; NEPHRECTOMY; CANCER prognosis
- Publication
In Vivo, 2021, Vol 35, Issue 2, p1083
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.12353