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- Title
Botulinum Toxin in Chronic Lateral Epicondylitis, from Tendon to Muscle Approach—A Review.
- Authors
Poenaru, Daniela; Sandulescu, Miruna Ioana; Potcovaru, Claudia-Gabriela; Cinteza, Delia
- Abstract
Background: Chronic lateral epicondylitis challenges the therapeutical approach; underlying mechanisms are incompletely understood; neuropathic pain and central and peripheral sensitization may explain the fact that botulinum toxin has been found to play a role in pain and function management. Methods: We searched the literature for MeSH terms: lateral epicondylitis or synonyms and botulinum toxin. Results: We found 14 papers containing trials on botulinum toxin injection into the tendon or into the extensor muscles (specifically, extensor carpi radialis brevis and extensor communis digitorum). We followed the administration pathways, doses, timing, and side effects. Conclusions: With a chronic course, the focus of the therapy shifts from the afflicted tendon to the inserting muscles, as muscle contracture may create a vicious loop to perpetuate and aggravate the disease. Doses, timing, and side effects are discussed.
- Subjects
BOTULINUM toxin; BOTULINUM A toxins; TENDONS; NEURALGIA; PAIN management; EXTENSOR muscles; INTRAMUSCULAR injections; WRIST
- Publication
Life (2075-1729), 2024, Vol 14, Issue 4, p528
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life14040528