We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Membranous and Membraneless Interfaces—Origins of Artificial Cellular Complexity.
- Authors
Stano, Pasquale; Tsumoto, Kanta
- Abstract
The review summarizes the factors that regulate phase separation, such as electrostatic interactions, chemical reactions, and membrane tension. The role of such knowledge on the synthetic cell perspective is highlighted (in particular, lateral phase separation can deform the membrane boundary and contribute to symmetry-breaking in very simple systems such as primitive cell models). Cells themselves are self-bounded compartments, limited by a lipid membrane; eukaryotic cells have internal membrane-bound organelles dedicated to specific cellular functions, such as the cell nucleus, mitochondria, chloroplasts, the endoplasmic reticulum, the Golgi apparatus, endosomes, lysosomes, etc. Shimokawa and Hamada [[25]] focused their review on the phenomenon of phase separation in membranes (the coexistence of liquid-ordered and liquid-disordered phases in the same membrane).
- Subjects
CHEMICAL reactions; SYNTHETIC biology; POLYMER blends; BIOLOGICAL systems; GOLGI apparatus; PHASE separation; CHLOROPLAST membranes; DEXTRAN
- Publication
Life (2075-1729), 2023, Vol 13, Issue 7, p1594
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life13071594