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- Title
HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies.
- Authors
Stefani, Chiara; Fantoni, Tobia; Bissoli, Michele; Thomas, Jordan; Ruggiero, Alessandra
- Abstract
Human immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century. Two major aspects of HIV-1 and SARS-CoV-2 co-infection have been extensively investigated and deserve attention. First, the impact of the co-infection on the progression of disease caused by HIV-1 or SARS-CoV-2. Second, the impact of the HIV-1 anti-retroviral treatment on SARS-CoV-2 infection. In this review, we aim to summarize and discuss the works produced since the beginning of the SARS-CoV-2 pandemic ranging from clinical studies to in vitro experiments in the context of co-infection and drug development.
- Subjects
SARS-CoV-2; CORONAVIRUSES; MIXED infections; HIV; ANTIRETROVIRAL agents
- Publication
Life (2075-1729), 2022, Vol 12, Issue 12, p2089
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life12122089