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- Title
Detection and correction of patient motion in dynamic <sup>15</sup>O-water PET MPI.
- Authors
Christensen, Nana L.; Nordström, Jonny; Madsen, Simon; Madsen, Michael A.; Gormsen, Lars C.; Kero, Tanja; Lubberink, Mark; Tolbod, Lars P.
- Abstract
Background: Patient motion constitutes a limitation to 15O-water cardiac PET imaging. We examined the ability of image readers to detect and correct patient motion using simulated motion data and clinical patient scans. Methods: Simulated data consisting of 16 motions applied to 10 motion-free scans were motion corrected using two approaches, pre-analysis and post-analysis for motion identification. Both approaches employed a manual frame-by-frame correction method. In addition, a clinical cohort was analyzed for assessment of prevalence and effect of motion and motion correction. Results: Motion correction was performed on 94% (pre-analysis) and 64% (post-analysis) of the scans. Large motion artifacts were corrected in 91% (pre-analysis) and 74% (post-analysis) of scans. Artifacts in MBF were reduced in 56% (pre-analysis) and 58% (post-analysis) of the scans. The prevalence of motion in the clinical patient cohort (n = 762) was 10%. Motion correction altered exam interpretation in only 10 (1.3%) clinical patient exams. Conclusion: Frame-by-frame motion correction after visual inspection is useful in reducing motion artifacts in cardiac 15O-water PET. Reviewing the initial results (parametric images and polar maps) as part of the motion correction process, reduced erroneous corrections in motion-free scans. In a large clinical cohort, the impact of motion correction was limited to few patients.
- Subjects
POSITRON emission tomography; INSPECTION &; review; CARDIAC imaging
- Publication
Journal of Nuclear Cardiology, 2023, Vol 30, Issue 6, p2736
- ISSN
1071-3581
- Publication type
Article
- DOI
10.1007/s12350-023-03358-5