We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Malignant cutaneous melanoma associated with neurofibromatosis in two sisters from a family with familial atypical multiple mole melanoma syndrome. Case reports and review of the literature.
- Authors
Stokkel, Marcel P. M.; Kroon, Bin B. R.; Van Der Sande, Jaap J.; Neering, Herman; Stokkel, M P; Kroon, B B; van der Sande, J J; Neering, H
- Abstract
Two cases of malignant melanoma associated with neurofibromatosis in two first-degree female relatives from a family with familial atypical multiple mole melanoma (FAMMM) syndrome are presented. The types of neurofibromatosis and the FAMMM syndrome are discussed in relation to these cases and the family genealogic tree. Although the FAMMM syndrome could probably be seen as the underlying disease in the current cases, review of literature has failed to establish a clear relation. Research into pigmentary disturbance in neurofibromatosis is necessary to give a final explanation. To our knowledge, this is the first report in literature describing the familial occurrence of both diseases and it might present an addition to the tumor spectrum in the FAMMM syndrome.
- Subjects
NEVUS; MELANOMA; SKIN tumors; MULTIPLE tumors; NEUROFIBROMATOSIS 1
- Publication
Cancer (0008543X), 1993, Vol 72, Issue 8, p2370
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19931015)72:8<2370::AID-CNCR2820720813>3.0.CO;2-R