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- Title
Hippocampal sclerosis is a progressive disorder: A longitudinal volumetric MRI study.
- Authors
Darren Fuerst; Jagdish Shah; Aashit Shah; Craig Watson
- Abstract
Twelve patients with refractory temporal lobe epilepsy and unilateral hippocampal sclerosis had repeat volumetric magnetic resonance imaging scans after a mean of 3.4 years to determine whether progressive hippocampal volume loss occurred. Seizure-free patients showed no change in hippocampal volume. Patients with continuing seizures had a decline in ipsilateral hippocampal volume that correlated with seizure frequency. Patients with medically refractory temporal lobe epilepsy and unilateral hippocampal sclerosis have progressive hippocampal atrophy. Ann Neurol 2003;53:413416
- Publication
Annals of Neurology, 2003, Vol 53, Issue 3, p413
- ISSN
0364-5134
- Publication type
Article