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- Title
Model systems for discovering evolutionary singularity of bilaterian physiological regulation: lessons from studies on simple/primitive flatworms.
- Authors
Shunsuke Mori; Aoshi Kobayashi; Hirotaka Sakamoto; Mayuko Hamada; Tatsuya Sakamoto; Ryo Nakamura
- Abstract
This article discusses the use of simple and primitive flatworms as model systems to study the evolutionary singularity of physiological regulation in bilaterian organisms. Bilaterians, which emerged around 550 million years ago, have diverse morphologies and physiologies, suggesting the existence of common mechanisms underlying their physiological processes. Flatworms, such as acoels and planarians, are considered to be positioned at the base of the evolutionary tree and exhibit characteristics that resemble the possible ancestral morphology of bilaterians. Studying these flatworms can provide insights into the evolutionary origins of physiological regulation in bilaterians. The article emphasizes the importance of integrating studies of newer and traditional model systems to gain a comprehensive understanding of evolutionary singularity.
- Subjects
CYCLIC-AMP-dependent protein kinase; CECUM; CENTRAL nervous system; CARDIOVASCULAR system; PROTEIN kinases
- Publication
Biophysics & Physicobiology, 2024, Vol 21, p1
- ISSN
2189-4779
- Publication type
Article
- DOI
10.2142/biophysico.bppb-v21.s012