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- Title
Daily oral intake of β-cryptoxanthin ameliorates neuropathic pain.
- Authors
Park, Gyujin; Horie, Tetsuhiro; Iezaki, Takashi; Okamoto, Maika; Fukasawa, Kazuya; Kanayama, Takashi; Ozaki, Kakeru; Onishi, Yuki; Sugiura, Minoru; Hinoi, Eiichi
- Abstract
β-cryptoxanthin, a xanthophyll carotenoid, exerts preventive effects on various lifestyle-related diseases. Here, we found that daily oral administration of β-cryptoxanthin significantly ameliorated the development of tactile allodynia following spinal nerve injury but was ineffective in mechanical allodynia in an inflammatory pain model in mice. Our results suggest that β-cryptoxanthin supplementation would be beneficial for the prophylaxis of neuropathic pain.
- Subjects
CRYPTOXANTHIN; PAIN management; DRUG efficacy
- Publication
Bioscience, Biotechnology & Biochemistry, 2017, Vol 81, Issue 5, p1014
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2017.1280661