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- Title
Ex vivo expansion of hematopoietic stem cells in bioreactors.
- Authors
Cabral, J. M. S.
- Abstract
The in vitro culture of human hematopoietic stem cells in different types of bioreactors is reviewed. After a brief description of the hematopoiesis and stem cells biology, the selection of growth medium for stem cells is evaluated as well as the parameters to be controlled for ex vivo expansion and differentiation of stem cells. Several types of bioreactors for in vitro stem cell culture are discussed and compared.
- Subjects
HEMATOPOIETIC stem cells; BONE marrow cells; BIOREACTORS; HEMATOPOIETIC system; CULTURES (Biology); BIOLOGY
- Publication
Biotechnology Letters, 2001, Vol 23, Issue 10, p741
- ISSN
0141-5492
- Publication type
Other
- DOI
10.1023/A:1010350215989