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- Title
Surgical outcomes of very-early-onset ulcerative colitis: retrospective comparative study with older pediatric patients.
- Authors
Fumita, Takashi; Terui, Keita; Shibata, Ryohei; Takenouchi, Ayako; Komatsu, Shugo; Oita, Satoru; Yoshizawa, Hiroko; Hirano, Yuichi; Yoshino, Yusaku; Saito, Takeshi; Hishiki, Tomoro
- Abstract
Purpose: The study compares the surgical outcomes of very-early-onset ulcerative colitis (VEO-UC), which is a rare disease diagnosed in pediatric patients < 6 years, with those of older pediatric patients with ulcerative colitis (UC). Methods: A retrospective observational study of 57 pediatric patients with UC was conducted at a single center. The study compared surgical complications and postoperative growth between the two groups. Results: Out of the 57 patients, 6 had VEO-UC, and 5 of them underwent total colectomy. Compared with the surgical cases of older patients with UC (n = 6), the rate of postoperative complications in patients with VEO-UC (n = 5) was not significantly different, except for high-output ileostomy (80% vs. 0% at 3 weeks postoperatively, p = 0.02). The rate of postoperative central venous catheter (CVC) placement at > 90 days was higher in patients with VEO-UC (100% vs. 17%, p = 0.02). The median change in the Z-score of height before and 2 years after colectomy was not significantly different between VEO-UC and older patients (1.1 vs. 0.3, p = 0.13). Conclusion: With regard to complications and outcomes, total colectomy for VEO-UC patients and that for older pediatric UC patients is comparable. However, high-output ileostomy and the long duration of CVC placement may pose management challenges.
- Subjects
CHILD patients; ULCERATIVE colitis; OLDER patients; INFLAMMATORY bowel diseases; CENTRAL venous catheters; SURGERY
- Publication
Pediatric Surgery International, 2024, Vol 40, Issue 1, p1
- ISSN
0179-0358
- Publication type
Article
- DOI
10.1007/s00383-024-05662-8